10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Leuprolide Acetate Leuprolide acetate (Leuprorelin) is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, ut
In vitro
Leuprolide acetate is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist. Leuprolide acetate suppresses gonadotrope secretion of luteinizing hormone and follicle-stimulating hormone that subsequently suppresses gonadal sex steroid production.
In vivo
Leuprolide acetate is used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization techniques. Leuprolide acetate is presently being tested for the treatment of Alzheimer\'s disease, polycystic ovary syndrome, functional bowel disease, short stature, premenstrual syndrome and even as an alternative for contraception. Leuprolide acetate is considered to be a very safe and tolerable drug.
Cell Data
cell lines：
Concentrations：10−6 M or 10−11 M
Incubation Time：6, 12, 18, 24 and 30 days.
Powder Purity:≥99%
| Isomere SMILES | CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6.CC(=O)O |
|---|---|
| Alternative CAS-Nummer | 53714-56-0 |
| Molekulargewicht | 1209.4（free base） |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Spezifische Drehung [α] | -34° (C=1,1%AcOH) |
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| 1. Ruoxin Wei, Jiaze Dou, Yihui Wu, Jinjin Li, Lian Cen, Zhenhao Xi. (2025) Microfluidic Regulation of Core–Shell PLGA Microspheres for Sustained Release of Leuprolide Acetate. LANGMUIR, [PMID:40605279] [10.1021/acs.langmuir.5c01667] |
