Mitogen-aktivierte Proteinkinase 3

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  1. 3,4-Dihydroxy-N-methyl-N-nitrosoaniline
    CAS: 173043-84-0 PubChem CID: 1607 Summenformel: C7H8N2O3 Molekulargewicht: 168.15
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: D667774
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    IUPAC-Bezeichnung
    N-(3,4-dihydroxyphenyl)-N-methylnitrous amide
    SMILES
    CN(C1=CC(=C(C=C1)O)O)N=O
    InChIKey
    XAKAQCMEMMZUEO-UHFFFAOYSA-N
    InChI
    1S/C7H8N2O3/c1-9(8-12)5-2-3-6(10)7(11)4-5/h2-4,10-11H,1H3
    Synonyme
    3,4-dephostatin | Me-3,4-dephostatin | Methyl-3,4-dephostatin | 3,4-Dihydroxy-N-methyl-N-nitrosoaniline | 4-[methyl(N...
  2. N-[5-(isopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide
    CAS: 1124381-69-6 PubChem CID: 59437537
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: N1330315
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    IUPAC-Bezeichnung
    N-[5-(propan-2-ylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]pyridine-3-carboxamide
    SMILES
    CC(C)NC1=CC(=CC2=NC(=NN12)NC(=O)C3=CN=CC=C3)C(F)(F)F
    InChIKey
    BDAJJFZKNIYDOL-UHFFFAOYSA-N
    InChI
    1S/C16H15F3N6O/c1-9(2)21-12-6-11(16(17,18)19)7-13-22-15(24-25(12)13)23-14(26)10-4-3-5-20-8-10/h3-9,21H,1-2H3,(H,23,24,26)
  3. 3-((6-((5-Chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
    CAS: 1316059-00-3 PubChem CID: 68304261
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: C980498
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    IUPAC-Bezeichnung
    3-[[6-[(5-chloropyridin-2-yl)amino]pyrimidin-4-yl]amino]-4-ethylsulfonyl-N-methylbenzenesulfonamide
    SMILES
    CCS(=O)(=O)C1=C(C=C(C=C1)S(=O)(=O)NC)NC2=NC=NC(=C2)NC3=NC=C(C=C3)Cl
    InChIKey
    OEDGERSSZUMLBI-UHFFFAOYSA-N
    InChI
    1S/C18H19ClN6O4S2/c1-3-30(26,27)15-6-5-13(31(28,29)20-2)8-14(15)24-17-9-18(23-11-22-17)25-16-7-4-12(19)10-21-16/h4-11,20H,3H2,1-2H3,(H2,21,22,23,24,25show more
  4. 7,3',4'-Trihydroxyisoflavone
    CAS: 485-63-2 EG-Nummer: 676-470-1 PubChem CID: 5284648 Summenformel: C15H10O5 Molekulargewicht: 270.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: T1495666
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  5. ASK1-IN-6
    CAS: 2407451-82-3 Summenformel: C17H14F4N6O2 Molekulargewicht: 410.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: A1498430
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  6. GSK854
    CAS: 1316059-00-3 PubChem CID: 68304261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: G1495212
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  7. GSK329
    CAS: 1268490-12-5 Summenformel: C19H14Cl2F3N5O2 Molekulargewicht: 472.25
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: G1495064
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  8. Pelubiprofen
    CAS: 69956-77-0 PubChem CID: 5282203
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: P1495552
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  9. Tpl2 Kinase Inhibitor 1
    CAS: 871307-18-5 EG-Nummer: 111-094-9 PubChem CID: 9549300 Summenformel: C21H14ClFN6 Molekulargewicht: 404.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: T1495533
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  10. TAK1-IN-3
    CAS: 494772-87-1 Summenformel: C16H19N3O2S Molekulargewicht: 317.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: T1494952
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  11. TC ASK 10
    CAS: 1005775-56-3 PubChem CID: 68661090 Summenformel: C21H21N5O.2HCl Molekulargewicht: 432.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Auf Bestellung · 8–12 Wochen Artikel #: T1493633
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Häufig gestellte Fragen

How is the MAP3K listing put together?
It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MAP3K modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MAP3K compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MAP3K compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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