Lornoxicam - 2mM in DMSO , CAS No.70374-39-9

CAS: 70374-39-9 Cat. No.: L425602 Summenformel: C₁₃H₁₀ClN₃O₄S₂ Molekulargewicht: 371.82 EG-Nummer: 630-354-7

GRADE & PURITY 2mM in DMSO

Synonyms

Lornoxicam|70374-39-9|Chlortenoxicam|Xefocam|Xefo|Lorcam|Lornoxicamum|Ro 13-9297|Lornoxicamum [INN-Latin]|Taigalor|Safem|Telos|Lorcam (TN)|CLTX|Lornoxicam (Xefo)|CCRIS 8589|NSC-759620|Ro-13-9297|6-chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Lornoxicam is a COX-1 and COX-2 inhibitor with IC50 of 5 nM and 8 nM, respectively.
A cyclooxygenase inhibitor.

Specifications

Synonyme

Lornoxicam | 70374-39-9 | Chlortenoxicam | Xefocam | Xefo | Lorcam | Lornoxicamum | Ro 13-9297 | Lornoxicamum [INN-Latin] | Taigalor | Safem | Telos | Lorcam (TN) | CLTX | Lornoxicam (Xefo) | CCRIS 8589 | NSC-759620 | Ro-13-9297 | 6-chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e

Spezifikationen & Reinheit

2mM in DMSO

Biochemische und physiologische Mechanismen

Lornoxicam is a cyclooxygenase inhibitor. Structurally similar to Tenoxicam. An anti-inflammatory and an analgesic. Lornoxicam is an inhibitor of Cox-1 and Cox-2.Potent COX-1 and COX-2 inhibitor (IC 50 = 5 and 8 nM for COX-1 and COX-2, respectively). Inhi

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Namen und Kennungen

• Kanonisches Lächeln: CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3
• IUPAC Name: 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide
• InChIKey: WLHQHAUOOXYABV-UHFFFAOYSA-N
• INCHI: 1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
• Isomere SMILES: CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3
• WGK Deutschland: 3
• RTECS: XJ9095000
• Molekulargewicht: 371.82
• Reaxy-Rn: 1039965
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1039965&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Ebene5 Amino acids and derivatives
          • Ebene6 Alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Alpha amino acids and derivatives
• Alternative Parents: Thienothiazines 2,3,5-trisubstituted thiophenes N-arylamides 1,2-thiazines Aryl chlorides Imidolactams Organosulfonamides Pyridines and derivatives Vinylogous acids Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Hydrocarbon derivatives Organic oxides Organochlorides Organopnictogen compounds Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-amino acid or derivatives - Thienothiazine - N-arylamide - 2,3,5-trisubstituted thiophene - Ortho-thiazine - Aryl chloride - Aryl halide - Organosulfonic acid amide - Pyridine - Imidolactam - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Vinylogous acid - Thiophene - Heteroaromatic compound - Secondary carboxylic acid amide - Carboxamide group - Azacycle - Organoheterocyclic compound - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
• External Descriptors: monocarboxylic acid amide - organochlorine compound - pyridines - heteroaryl hydroxy compound - thienothiazine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Heat sensitive
• Schmelzpunkt (°C): 230°C
• Molekulargewicht: 371.800 g/mol
• XLogP3: 2.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 370.98 Da
• Monoisotopic Mass: 370.98 Da
• Topological Polar Surface Area: 136.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 634.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referenzen

1. Junjing Li, Xu Liu, Zilin Tan, Liang Wang.  (2025)  Performance and mechanism of palladium-based binary nanowires for electrocatalytic removal of halogenated PPCPs.  Surfaces and Interfaces,      [PMID:] [10.1016/j.surfin.2025.106188]

2. Wei Shao, Xiuling Liu, Zhaojing Jing, Ziyang Guo, Xiaowen Huo, Weihao Zhang, Haitao Wang, Na Chang.  (2026)  Ionic interactions drive SC[4]A to regulate polyamide networks for achieving high-efficiency Li+/Mg2+ separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2026.137014]

Häufig gestellte Fragen

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 70374-39-9, the molecular formula is C13H10ClN3O4S2, and the molecular weight is 371.82 g/mol. InChIKey WLHQHAUOOXYABV-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.