Lumasiran - ≥95% , CAS No.1834610-13-7

CAS: 1834610-13-7 Cat. No.: L647658 Molekulargewicht: 16339.00 (AS: 7631.0 +SS: 8708.0)

QUALITÄT & REINHEIT ≥95%

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Übersicht

Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1).

In Vitro

Lumasiran reduced urinary oxalate excretion, the cause of progressive kidney failure in PH1. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Lumasiran is a subcutaneously administered, liver-directed RNA interference (RNAi) therapeutic agent. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Spezifikationen

Spezifikationen & Reinheit

≥95%

Biochemische und physiologische Mechanismen

Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase . By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the to

Storage

Store at -20°C,Argon charged,Desiccated

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥95%

Namen und Kennungen

Kanonisches Lächeln

[Lumasiran]

Molekulargewicht

16339.00 (AS: 7631.0 +SS: 8708.0)

Chemische und physikalische Eigenschaften

• Löslichkeit: H2O : 100 mg/mL (Need ultrasonic)

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1834610-13-7, and the molecular weight is 16339.00 (AS: 7631.0 +SS: 8708.0) g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.