luminol - 10mM in DMSO , CAS No.521-31-3

CAS: 521-31-3 Cat. No.: L424466 Summenformel: C₈H₇N₃O₂ Molekulargewicht: 177.16 Beilstein Registry Number: 383929 EG-Nummer: 208-309-4

QUALITÄT & REINHEIT 10mM in DMSO

Synonyms

LUMINOL|3-Aminophthalhydrazide|521-31-3|5-amino-2,3-dihydrophthalazine-1,4-dione|5-Amino-2,3-dihydro-1,4-phthalazinedione|3-Aminophthalic hydrazide|1,4-Phthalazinedione, 5-amino-2,3-dihydro-|5-Amino-1,2,3,4-tetrahydrophthalazine-1,4-dione|3-Aminophthalylh

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Luminol is a reagent for the generation of chemiluminescence in biological assays including nitric oxide and myeloperoxidase assay. Luminol is converted to a dianion in basic solution, which is then oxidized with H2O2/Cu2+ to form N2 and an aminophthalate ion in an electronically excited state. The aminophthalate ion emits a photon of wavelength 424 nm.
A chemiluminescence generating reagent for biological and metal cation assays

Spezifikationen

Synonyme

LUMINOL | 3-Aminophthalhydrazide | 521-31-3 | 5-amino-2,3-dihydrophthalazine-1,4-dione | 5-Amino-2,3-dihydro-1,4-phthalazinedione | 3-Aminophthalic hydrazide | 1,4-Phthalazinedione, 5-amino-2,3-dihydro- | 5-Amino-1,2,3,4-tetrahydrophthalazine-1,4-dione | 3-Aminophthalylh

Spezifikationen & Reinheit

10mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Namen und Kennungen

Pubchem Sid

528776636

Kanonisches Lächeln

C1=CC2=C(C(=C1)N)C(=O)NNC2=O

IUPAC Name

5-amino-2,3-dihydrophthalazine-1,4-dione

InChIKey

HWYHZTIRURJOHG-UHFFFAOYSA-N

INCHI

1S/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13)

Isomere SMILES

C1=CC2=C(C(=C1)N)C(=O)NNC2=O

WGK Deutschland

3

RTECS

TH8890060

Molekulargewicht

177.16

Beilstein

383929

Reaxy-Rn

383929

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=383929&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Diazanaphthalenes
      • Subclass Benzodiazines
        • Ebene5 Phthalazines
          • Ebene6 Phthalazinones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Phthalazines
• Direct Parent: Phthalazinones
• Alternative Parents: Pyridazinones Benzenoids Vinylogous amides Heteroaromatic compounds Lactams Azacyclic compounds Primary amines Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Phthalazinone - Pyridazinone - Pyridazine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Lactam - Azacycle - Amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary amine - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as phthalazinones. These are compounds containing a phthalazine bearing a ketone group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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TNF Tclin TNF-alpha (1897 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)

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Hdac6 Histone deacetylase 6 (222 Activities)

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Qtrt1 tRNA-guanine transglycosylase (21 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

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Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Air Sensitive
• Schmelzpunkt (°C): ≥300°C
• Molekulargewicht: 177.160 g/mol
• XLogP3: 0.300
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 177.054 Da
• Monoisotopic Mass: 177.054 Da
• Topological Polar Surface Area: 84.200 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 254.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1