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· · COA & SDS für jedes Produkt verfügbar · Versand am selben Tag auf Lager LY2940680 - Moligand™, 2mM in DMSO , Smoothened homolog antagonist, CAS No.1258861-20-9, Smoothened homolog antagonist
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO Synonyms
CCG-269788 | BCP9000881 | DTXSID50154986 | Taladegib (LY2940680) | EX-A156 | LY 2940680 | NCGC00263170-06 | J-515412 | 1258861-20-9 | DB12550 | UNII-QY8BWX1LJ5 | 1KS | IEISBKIVLDXSMZ-UHFFFAOYSA-N | MFCD21609264 | R06AD04 | Taladegib | HMS2230I06 | LY29406
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 2mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht LY2940680 binds to the Smoothened (Smo) receptor and potently inhibits Hedgehog (Hh) signaling. Phase 1/2.
Specifications Synonyme
CCG-269788 | BCP9000881 | DTXSID50154986 | Taladegib (LY2940680) | EX-A156 | LY 2940680 | NCGC00263170-06 | J-515412 | 1258861-20-9 | DB12550 | UNII-QY8BWX1LJ5 | 1KS | IEISBKIVLDXSMZ-UHFFFAOYSA-N | MFCD21609264 | R06AD04 | Taladegib | HMS2230I06 | LY29406
Spezifikationen & Reinheit
Moligand™, 2mM in DMSO
Biochemische und physiologische Mechanismen
Potent Hedgehog signaling pathway inhibitor. Smoothened antagonist. Inhibits growth of cancer cell lines containing a disease-relevant\xa0Smoothened gene mutation. Has anti-tumor activity in animal models.
Verschickt in
Dry ice packs + Cold packs
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Mechanismus der Wirkung
Smoothened homolog antagonist
Produkteigenschaften Namen und Kennungen Pubchem Sid 528765350 Kanonisches Lächeln CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F IUPAC Name 4-fluoro-N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-2-(trifluoromethyl)benzamide InChIKey SZBGQDXLNMELTB-UHFFFAOYSA-N INCHI 1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3 Isomere SMILES CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F Molekulargewicht 512.5 Reaxy-Rn 20922603 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20922603&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Klasse Diazanaphthalenes Subclass Benzodiazines Intermediate Tree Nodes Not available Direct Parent Phthalazines Alternative Parents Trifluoromethylbenzenes 4-halobenzoic acids and derivatives Benzamides Dialkylarylamines Benzoyl derivatives Aminopyridazines Fluorobenzenes Piperidines Aryl fluorides Imidolactams Tertiary carboxylic acid amides Pyrazoles Heteroaromatic compounds Azacyclic compounds Organooxygen compounds Organic oxides Organofluorides Alkyl fluorides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Trifluoromethylbenzene - Phthalazine - 4-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - Benzamide - Benzoic acid or derivatives - Benzoyl - Dialkylarylamine - Aminopyridazine - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Imidolactam - Piperidine - Pyridazine - Benzenoid - Tertiary carboxylic acid amide - Pyrazole - Azole - Heteroaromatic compound - Carboxamide group - Azacycle - Carboxylic acid derivative - Alkyl halide - Hydrocarbon derivative - Organic oxide - Amine - Organic oxygen compound - Organohalogen compound - Organooxygen compound - Organic nitrogen compound - Organofluoride - Alkyl fluoride - Organonitrogen compound - Aromatic heteropolycyclic compound Beschreibung This compound belongs to the class of organic compounds known as phthalazines. These are compounds containing a phthalazine moiety, which consists of a benzene ring fused to a pyridazine, forming a 2,3-benzodiazine skeleton. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Molekulargewicht 512.500 g/mol XLogP3 4.300 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 9 Rotatable Bond Count 4 Exact Mass 512.195 Da Monoisotopic Mass 512.195 Da Topological Polar Surface Area 67.200 Ų Heavy Atom Count 37 Formal Charge 0 Complexity 794.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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View Moligand™ grade guide →
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