Manganese standard - analytical standard, 1.32mg/L in H2O , CAS No.7439-96-5

CAS: 7439-96-5 Cat. No.: M301087 Summenformel: Mn Molekulargewicht: 54.94 EG-Nummer: 231-105-1 PubChem CID: 23930

QUALITÄT & REINHEIT Analytical standard, 1.32mg/L in H2O

Synonyms

Manganese(4 ) | Magnacat | Manganese, rod, 35mm, diameter 2.0mm, cast, 99.5% | Manganese, rod, length 25 mm, 2.0 mm diameter, purity 99.5% | Mn(0) | MNE 06PB | CHEBI:25158 | Manganese, rod, 10mm, diameter 4.0mm, cast, 99.5% | MANGANUM METALLICUM [HPUS] |

Storage

Room temperature

Shipped In

FedEx DG Service

Spezifikationen

Synonyme

Manganese(4 ) | Magnacat | Manganese, rod, 35mm, diameter 2.0mm, cast, 99.5% | Manganese, rod, length 25 mm, 2.0 mm diameter, purity 99.5% | Mn(0) | MNE 06PB | CHEBI:25158 | Manganese, rod, 10mm, diameter 4.0mm, cast, 99.5% | MANGANUM METALLICUM [HPUS] |

Spezifikationen & Reinheit

analytical standard, 1.32mg/L in H2O

Storage

Room temperature

Verschickt in

FedEx DG Service

Note

Analytischer Standard

Namen und Kennungen

Kanonisches Lächeln

[Mn]

IUPAC Name

manganese

InChIKey

PWHULOQIROXLJO-UHFFFAOYSA-N

INCHI

1S/Mn

Isomere SMILES

[Mn]

PubChem CID

23930

UN-Nummer

3089(powder)

Verpackungsgruppe

II

Molekulargewicht

54.94

Taxonomic Classification

Taxonomy Tree

• Kingdom Inorganic compounds
  • Superclass Homogeneous metal compounds
    • Klasse Homogeneous transition metal compounds

• Kingdom: Inorganic compounds
• Superclass: Homogeneous metal compounds
• Klasse: Homogeneous transition metal compounds
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Homogeneous transition metal compounds
• Alternative Parents: Not available
• Molecular Framework: Not available
• Substituents: Homogeneous transition metal
• Beschreibung: This compound belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
• External Descriptors: elemental manganese

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Siedepunkt (°C): 2095°C
• Schmelzpunkt (°C): 1244°C
• Molekulargewicht: 54.938 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 54.938 Da
• Monoisotopic Mass: 54.938 Da
• Topological Polar Surface Area: 0.000 Ų
• Heavy Atom Count: 1
• Formal Charge: 0
• Complexity: 0.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3

Application Protocols

No item-specific tested applications are provided for this SKU.

General example protocols (analytical; not item-specific)

• ICP-MS multi-point calibration
  • Prepare a series of working standards (e.g., 0, 0.5, 1, 5, 10, 50 µg/L Mn) by gravimetric dilution of the stock manganese standard into 1–2% HNO3 (or matrix per CoA).
  • Include an internal standard at constant concentration across all solutions.
  • Acquire data, fit calibration (weighted if heteroscedastic), and verify with an independent check standard.
• AAS calibration (flame)
  • Select an appropriate analytical line (e.g., 279.5 nm). Prepare standards bracketing sample concentrations in matched acid. Run blanks between high-level standards to minimize carryover.
• Stability/adsorption check
  • Store an aliquot of a low-level standard in your intended container. Analyze at t0 and after 24–72 h to evaluate adsorption losses. Adjust acid strength or container type accordingly.

For this SKU’s exact concentration, matrix, and certified uncertainty: Not specified for this item; refer to CoA/Spec Sheet.

Biological Roles

General information (biochemistry; not item-specific)

• Manganese is an essential trace element in biology, functioning predominantly in the +2 oxidation state. It serves as a cofactor in numerous enzymes, including superoxide dismutase (MnSOD), arginase, and enzymes of carbohydrate and amino acid metabolism (literature).
• Mn participates in redox processes and is critical for the oxygen-evolving complex of photosystem II in plants (higher oxidation states, e.g., Mn3+/Mn4+, literature).
• Homeostasis is tightly regulated via transporters and metallochaperones; imbalance can cause deficiency or toxicity at the organismal level. These are biological context notes and do not imply any clinical or diagnostic application for this product.

Analytical relevance

• Knowledge of biological roles underpins the need to quantify Mn in environmental, food, and biological samples. Calibration standards like this product support trace-level determinations in such matrices by ICP-MS/ICP-OES/AAS.

Important use note

• This product is labeled For research use only (from Product Data). It is not intended for human or animal diagnostic or therapeutic use. No medical or clinical claims are made or implied.

Buffer Applications

Not typically applicable.

• Manganese standards are not used as buffering agents. They are calibration solutions for elemental analysis.

Practical adjacent guidance

• For preparing calibration and sample diluents, use high-purity water with a defined acid matrix (e.g., nitric acid) to control pH and ionic strength. This is done to maintain Mn solubility and matrix match to instrument conditions, not to buffer at a specific pH.
• If method protocols specify a background electrolyte (e.g., in capillary electrophoresis studies of metal complexes), prepare buffers separately and spike with Mn standard as needed, verifying complexation and stability under those conditions.

Green Alternatives

Context

• As a calibration standard, environmental impact considerations focus on minimizing acid use, waste generation, and plastic consumption rather than substituting a different “reagent.”

Greener practice options (general)

• Minimize volumes: Prepare only the calibration range needed for a run; scale working standards to daily demand to reduce discard of expired solutions.
• Matrix optimization: Use the lowest acid concentration that maintains stability and compatibility with the instrument to reduce corrosivity and neutralization waste.
• Reusable containers: Where contamination control allows, employ rigorously acid-cleaned, reusable fluoropolymer bottles instead of single-use plastics.
• Waste management: Segregate acidic metal-bearing waste for appropriate treatment/recovery. Neutralize cautiously and capture Mn-containing residues for hazardous waste disposal.
• Multi-element mixes: For high-throughput labs with many analytes, validated multi-element standards can reduce the number of containers and shipments, lowering packaging and transport footprint, though they may have shorter stability windows.

Trade-offs

• Lower acid content decreases hazard and waste neutralization demand but may increase adsorption losses at ultra-trace levels. Balance stability with environmental impact through verification studies (e.g., low-level recovery tests over time).
• Reuse of containers reduces waste but increases risk of cross-contamination; implement validated cleaning protocols and QC checks.

Note: The specific matrix and concentration for this SKU are Not specified for this item; refer to CoA/Spec Sheet; adapt the above practices accordingly.

Pharmaceutical Uses

Formulation/manufacturing context (general; no therapeutic claims)

• Elemental impurity control: Manganese is one of the elemental impurities monitored under ICH Q3D and USP <232>/<233>. Single-element Mn standards are used to calibrate ICP-MS/ICP-OES methods for drug substance/product testing and for excipient qualification. This product, labeled Analytical standard, is suitable for laboratory calibration activities when accompanied by appropriate documentation and traceability; specific certification details are Not specified for this item; refer to CoA/Spec Sheet.
• System suitability and QC: Used for calibration curves, independent check standards, and spike recovery experiments in GMP/GLP settings, subject to laboratory qualification and method validation.

Operational considerations

• Matrix matching with sample digest acid (commonly HNO3) supports accurate quantitation and mitigates transport/ionization effects in plasma-based techniques.
• Document lot traceability, uncertainty, and expiration. Store at Room temperature as specified, unless the CoA indicates otherwise.

Regulatory note

• For research use only (from Product Data). Additional qualification may be required before use in regulated QC environments. Consult your quality unit to ensure suitability and documentation (traceability, uncertainty, stability) meet applicable pharmacopeial and ICH expectations.

Physical Properties

Item-specific specifications

• Appearance: Not specified for this item; refer to CoA/Spec Sheet.
• Concentration, matrix, stabilizer, and pH: Not specified for this item; refer to CoA/Spec Sheet.
• Density, refractive index, water/metal/peroxide impurities: Not specified for this item; refer to CoA/Spec Sheet.

Literature/general physical data (for context; not item specifications)

• Elemental manganese (Mn, CAS 7439-96-5):
  • Melting point: ~1246 °C (literature)
  • Boiling point: ~2061 °C (literature)
  • Density (20 °C): ~7.21 g/cm3 (literature)
  • Solubility: Insoluble in water as metal; soluble upon conversion to salts (literature)
• Aqueous Mn2+ calibration standards (general):
  • Typically supplied in high-purity water with ~1–5% nitric or hydrochloric acid to prevent adsorption/precipitation; exact matrix varies by product (literature). For this item: Not specified; refer to CoA/Spec Sheet.
  • Partition coefficients (logP) and refractive index are not typically defined for such dilute inorganic salt solutions.

Notes for users

• Physical behavior (viscosity, density) of a manganese standard depends strongly on the acid matrix and concentration. For precise volumetric corrections (e.g., in gravimetric dilutions), use the certificate-provided density and concentration if available. Absent that, prepare dilutions gravimetrically using high-purity water and appropriate acid to maintain matrix compatibility with your analytical method.

Quality and Grades

Item-specific grade

• Grade/Purity: Analytical standard (from Product Data).

What “Analytical standard” implies (general)

• Intended use: Calibration and quality control for instrumental analysis (e.g., ICP-MS, ICP-OES, AAS) and method validation. Such materials emphasize traceability, defined concentration, minimal contamination, and stability, rather than synthetic reagent purity.
• Traceability: High-quality standards are typically traceable to national metrology institutes (e.g., NIST) or accredited reference materials and accompanied by a certificate that states the certified value, uncertainty, and measurement traceability. For this SKU, certificate details are Not specified for this item; refer to CoA/Spec Sheet.
• Matrix and stabilizers: Acid matrix (often HNO3 or HCl) minimizes adsorption/precipitation and provides shelf stability. Exact matrix and stabilizers for this item are Not specified for this item; refer to CoA/Spec Sheet.
• Impurities: Critical impurity metrics for calibration standards include other trace metals, anions, and carbon. Specific impurity limits for this item are Not specified for this item; refer to CoA/Spec Sheet.

Practical guidance

• Use class-A volumetric ware or gravimetric dilutions with high-purity water (18.2 MΩ·cm) to prepare working standards.
• Employ matrix matching for accurate quantitation (same acid type/strength and total dissolved solids as samples and calibration blanks).
• Record lot number, opening date, and maintain documentation for audits and method validation.

Reaction and Applications

This product is intended for analytical calibration rather than as a reactant in synthetic chemistry.

Analytical applications (general/literature)

• ICP-MS and ICP-OES calibration: Prepare multi-point calibration curves across the expected Mn concentration range (e.g., ng/L to mg/L) using gravimetric dilutions in matrix-matched diluent. Verify linearity (r2 ≥ 0.999) and monitor an internal standard (e.g., Sc, Y, or In) for drift correction.
• AAS calibration: Use appropriate flame or graphite furnace conditions; match acid concentration to standards to reduce nebulization and atomization biases.
• Quality control: Include continuing calibration verification (CCV), independent check standards (ICS), and laboratory control samples (LCS) to confirm accuracy. Conduct spike recoveries in representative matrices.
• Standard additions: For complex matrices prone to matrix effects, employ standard addition to the sample aliquots to improve accuracy.
• Digestion/pretreatment context: In total metal analyses, samples are typically digested (e.g., hot block with HNO3/H2O2 or microwave digestion) prior to measurement; the Mn standard is used only for calibration, not digestion.

Practical tips

• Use acid-cleaned labware and verify blanks (procedural and instrument) below the lowest calibration level.
• Allow standards to equilibrate to room temperature before volumetric work; perform gravimetric dilutions when feasible to minimize temperature-related density errors.
• Track bottle open time; replace working standards regularly to mitigate adsorption or contamination. For this item’s specific shelf-life and use window: Not specified; refer to CoA/Spec Sheet.

Reaction Conditions

Analytical calibration conditions (general guidance; not item-specific)

• Instrumentation: ICP-MS/ICP-OES/AAS.
• Typical calibration ranges: Method-dependent; for environmental waters often 0.1–100 µg/L; for nutraceuticals/foods/pharma digests often 1–1000 µg/L. Select a range that brackets expected sample concentrations and meets instrument linearity (literature/best practice).
• Diluents: High-purity water with acid matching the stock standard (e.g., 1–2% HNO3 v/v). For this item’s exact matrix: Not specified; refer to CoA/Spec Sheet.
• Internal standards (ICP-MS): Elements with similar mass/ionization behavior and absent from samples (e.g., Sc-45, Y-89, In-115) are common choices; validate for your matrix.
• Interferences: Spectral overlaps in ICP-OES (line selection) and polyatomics in ICP-MS (e.g., 40Ar15N+ near m/z 55; instrument CRC modes mitigate). Optimize nebulizer gas, RF power, and CRC settings per instrument manual.
• QC scheme: Include calibration blanks, continuing calibration verification (every 10–20 samples), independent check standards, method blanks, and matrix spikes. Acceptance criteria based on your method (e.g., CCV within ±10%).

Notes

• Use gravimetric preparation for highest accuracy and uncertainty control.
• Equilibrate solutions to lab temperature; swirl gently to homogenize. Rinse introduction system with matrix-matched solution before acquisition to minimize memory effects.

Safety and Handling

Item-specific hazard data

• GHS classification, signal word, pictograms, H-statements: Not specified for this item; refer to SDS.
• Storage conditions: Room temperature (from Product Data).
• Shipping: FedEx DG Service (from Product Data), indicating hazardous material handling in transport.

General safety guidance (not item-specific; consult SDS for your lot)

• Likely hazards by product type: Commercial manganese analytical standards are commonly acidified (e.g., HNO3 or HCl) and can be corrosive to skin/eyes and metals; manganese salts can be harmful if swallowed or inhaled. Avoid aerosol generation and ingestion (literature).
• PPE: Laboratory coat, safety glasses or face shield, and acid-resistant gloves (e.g., nitrile). Use a fume hood when handling concentrates or preparing dilutions.
• Incompatibilities: Avoid contact with bases (neutralization heat), reactive metals, cyanides (possible HCN formation in strong acid), and oxidizable organics when strong oxidizing acids are present. Keep away from reducing agents that could alter oxidation state and from carbonate sources that may induce precipitation (literature).
• First aid overview: Rinse skin/eyes with copious water for ≥15 minutes if exposed. If inhaled, move to fresh air. If ingested, do not induce vomiting; seek medical attention. Always follow your institution’s emergency procedures.
• Spill/response: Neutralize small acidic spills cautiously with sodium bicarbonate while controlling heat and CO2 evolution. Absorb with inert material. For trace-metal standards, prevent environmental release and collect as hazardous waste.

Always defer to the current SDS/CoA for definitive hazard and handling information.

Solvent Selection

Applicability to this product

• As an “Analytical standard,” this item is typically provided as an aqueous solution. Exact solvent and acid matrix are Not specified for this item; refer to CoA/Spec Sheet.

General guidance (literature/practice)

• Polarity/miscibility: Aqueous, fully miscible with water; acidified matrices are common to maintain Mn in solution and minimize adsorption losses on container walls.
• Diluents for calibration: Use high-purity water (18.2 MΩ·cm) and the same acid (type and molarity) as the stock standard and instrument rinse solution to maintain matrix consistency and improve accuracy in ICP-MS/ICP-OES/AAS.
• Container compatibility: Prefer low-adsorption, acid-cleaned fluoropolymer (FEP, PTFE) or high-quality PP/PE bottles for low-level work. Avoid borosilicate glass for sub-ppb Mn due to potential leaching/adsorption unless acid-washed and verified.

Choosing among alternatives

• Nitric-acid matrix vs HCl matrix: HNO3 is broadly compatible with ICP-MS and minimizes chloride-related polyatomic interferences; HCl matrices can be advantageous for certain sample types but may introduce ArCl+ interferences in ICP-MS at m/z 55 (mitigated by collision/reaction cell). Select based on method and instrument configuration.
• Single-element vs multi-element standards: Single-element Mn standards simplify preparation and reduce inter-element interactions at ultra-trace levels; multi-element mixes are convenient for routine calibration but require careful consideration of stability and interferences.

For this SKU, consult the CoA to confirm matrix, concentration, and any stabilizers before preparing dilutions.

Storage and Reconstitution

Item-specific

• Storage conditions: Room temperature (from Product Data). Avoid temperature extremes; store tightly closed.
• Shipped in: FedEx DG Service (from Product Data).
• Reconstitution: Not applicable—typically supplied ready-to-use as a liquid standard. If this item is a solid (not indicated), reconstitution details are Not specified for this item; refer to CoA/Spec Sheet.

General handling for calibration standards

• Upon receipt, document lot number and certificate. Do not pipette from the original bottle when preparing low-level standards—pour an aliquot into a clean secondary container to avoid contamination.
• Homogenize by gentle inversion before use; avoid vigorous shaking that can introduce bubbles and volumetric errors.
• After opening, record the date; for working dilutions, label concentration, matrix, and preparation date. Replace working standards periodically based on stability studies or institutional SOPs.

Container/materials

• Use acid-cleaned fluoropolymer or PP/PE labware for sub-ppb work. Rinse all ware with matrix acid before use.

Shelf life and specs

• Expiry date, certified value, and uncertainty: Not specified for this item; refer to CoA/Spec Sheet.
• Research Use Note: For research use only (from Product Data).

Structure and Identity

Item-specific (from Product Data)

• Product: Manganese standard (Analytical standard)
• CAS: 7439-96-5
• CID: 23930
• InChIKey: 288685 (as provided)
• SMILES: Not specified for this item; refer to CoA/Spec Sheet.
• Molecular formula: Not specified for this item; refer to CoA/Spec Sheet.
• Molecular weight: Not specified for this item; refer to CoA/Spec Sheet.

Literature/general identifiers and structural notes (for reference only)

• Element: Manganese (Mn), atomic number 25
• Molecular (atomic) weight (IUPAC 2013): 54.938 g/mol (literature)
• SMILES (elemental): [Mn] (literature)
• InChIKey (elemental): PWHULOQIROXLJO-UHFFFAOYSA-N (literature)
• Structural features: As an element, manganese does not possess covalent functional groups. In standards, manganese is typically present as Mn2+ in an aqueous, acidified matrix for trace analysis; the exact oxidation state and counterion for this item are not specified.

2D/chemical description

• Elemental manganese is a first-row transition metal with common oxidation states +2, +3, +4, +6, and +7 (literature). Analytical calibration standards generally deliver Mn in the +2 state for ICP-OES/ICP-MS/AAS. For this SKU, the exact species, concentration, and matrix are Not specified for this item; refer to CoA/Spec Sheet.

Synthetic Utility

Not a synthetic building block in this product form.

Contextual notes (general)

• While manganese compounds play roles in synthesis (e.g., MnO2 oxidations, Mn(III)-mediated radical reactions, Mn-catalyzed C–H functionalization), an “Analytical standard” is not intended for preparative chemistry. Its value lies in delivering a certified amount of Mn for instrumental calibration.
• If conversion to a reagent is contemplated (e.g., precipitating a salt), this would fall outside typical use and could compromise traceability and certification. For accurate analyses, use the standard solely for calibration/QA tasks.

Takeaway

• Use this item to establish measurement traceability for Mn, not as a stoichiometric reagent or catalyst.

Target Specificity

Not applicable.

• This product is a chemical calibration standard, not a biological affinity reagent (e.g., antibody, ligand). No antigen/epitope/clone/isotype information exists for this SKU.