≥85% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Lagerung bei -20°C Ships Eistruhe + Eispads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Meclocyclin ist ein halbsynthetisches Tetracyclin, das durch Dehydratisierung der 6-Hydroxygruppe von Chlortetracyclin zu einem exocyclischen 6-Methylen hergestellt wird. Meclocylin ist ein enges strukturelles Analogon von Methacyclin. Wie alle Tetracycline zeigt Meclocyclin ein breites Spektrum an antibakterieller und antiprotozoischer Aktivität und wirkt durch Bindung an die ribosomalen Untereinheiten 30S und 50S, wodurch die Proteinsynthese blockiert wird.
| pKa | pKa: 4.5 (Predicted), pKa: 10.72 (Predicted) |
|---|
| Pubchem Sid | 528773528 |
|---|---|
| Kanonisches Lächeln | CN(C)C1C2C(C3C(=C)C4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O |
| IUPAC Name | (4S,4aR,5S,5aR,12aR)-7-chloro-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide |
| InChIKey | RNIADBXQDMCFEN-IWVLMIASSA-N |
| INCHI | 1S/C22H21ClN2O8/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30/h4-5,10,14-15,17,26-28,31,33H,1H2,2-3H3,(H2,24,32)/t10-,14-,15+,17+,22+/m1/s1 |
| Isomere SMILES | CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O |
| RTECS | QI7830000 |
| Molekulargewicht | 476.86 |
| Reaxy-Rn | 25809060 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25809060&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Klasse | Tetracyclines |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Tetracyclines |
| Alternative Parents | Naphthols and derivatives 1-hydroxy-2-unsubstituted benzenoids Cyclohexenones Aryl chlorides Vinylogous acids Tertiary alcohols Trialkylamines Secondary alcohols Cyclic alcohols and derivatives Enols Polyols Carboximidic acids Hydrocarbon derivatives Organopnictogen compounds Organic oxides Organochlorides |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | Tetracycline - 1-naphthol - Naphthalene - 1-hydroxy-2-unsubstituted benzenoid - Cyclohexenone - Aryl chloride - Aryl halide - Benzenoid - Cyclic alcohol - Tertiary alcohol - Vinylogous acid - Cyclic ketone - Tertiary amine - Tertiary aliphatic amine - Secondary alcohol - Ketone - Polyol - Carboximidic acid - Carboximidic acid derivative - Enol - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organohalogen compound - Organochloride - Alcohol - Organonitrogen compound - Organooxygen compound - Carbonyl group - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic homopolycyclic compound |
| Beschreibung | This compound belongs to the class of organic compounds known as tetracyclines. These are polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Datum | Artikel |
|---|---|---|---|
 C2507496 | Certificate of Analysis | Oct 25, 2024 | M329461 |
| Löslichkeit | Soluble in ethanol, methanol, DMF, DMSO. Limited water solubility. |
|---|---|
| Empfindlichkeit | Light sensitive |
| Brechungsindex | n20D1.76 (Predicted) |
| Siedepunkt (°C) | ~837.0° C at 760 mmHg (Predicted) |
| Schmelzpunkt (°C) | 339.97° C (Predicted) |
| Molekulargewicht | 476.900 g/mol |
| XLogP3 | 0.900 |
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 2 |
| Exact Mass | 476.099 Da |
| Monoisotopic Mass | 476.099 Da |
| Topological Polar Surface Area | 182.000 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 1040.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
