GRADE & PURITY 10mM in DMSO

Synonyms

1-​deoxy-​1-​(methylamino)​-D-​glucitol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Meglumine is an amino sugar derived from sorbitol for THP-1 cells with IC50 of 22 μg/mL.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥100%

Specifications

Synonyms

1-​deoxy-​1-​(methylamino)​-D-​glucitol

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Meglumine is an amino sugar derived from sorbitol for THP-1 cells with IC50 of 22 μg/mL.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
• WGK Germany: 3
• Alternate CAS: 90191-92-7
• Molecular Weight: 195.21
• Beilstein: 385906
• Reaxy-Rn: 2324336
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2324336&ln=

Chemical and Physical Properties

• Specific Rotation[α]: -16.5 ° (C=2, H2O)
• Boil Point(°C): 210 °C/1013 hPa
• Melt Point(°C): 129-131.5 °C (lit.)

References

1. Wenqing Wang, Hao Li, Yongquan Zhou, Jianming Pan.  (2023)  Investigation of the mechanism of establishing a solid–water–oil system by metastable droplets and their application in the fabrication of polyol nanosheets for rapid boron removal.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.145930]

2. Kong Ruiping, Xu Lingwei, Zhu Li, Sun Yongrong.  (2023)  Preparation, characterization and evaluation of cefixime ternary inclusion complexes formated by mechanochemical strategy.  JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY,      [PMID:] [10.1007/s10847-023-01214-0]

3. Tongtong Pan, Xiangmei Cui.  (2023)  Gelatin aerogel with good mechanical properties and adjustable physical properties for boron adsorption from salt lake brines: An optimized process.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37597634] [10.1016/j.ijbiomac.2023.126403]

4. Guolong Huang, Yifan Qiu, Lei Bi, Huiyi Wei, Guocong Li, Zhijun Li, Peizhen Ye, Min Yang, Yanfang Shen, Hao Liu, Lu Wang, Hongjun Jin.  (2022)  PET Imaging of P2X7 Receptor (P2X7R) for Neuroinflammation with Improved Radiosynthesis of Tracer [18F]4A in Mice and Non-human Primates.  ACS Chemical Neuroscience,      [PMID:36441909] [10.1021/acschemneuro.2c00506]

5. Chun Bai, Kexin Li, Dezhen Fang, Xiushen Ye, Huifang Zhang, Quan Li, Jun Li, Haining Liu, Zhijian Wu.  (2021)  Efficient separation of boron from salt lake brine using a novel flotation agent synthesized from NMDG and 1-bromooctadecane.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2021.127178]

6. Mei Hong, Die Li, Bingyu Wang, Jingyu Zhang, Bin Peng, Xiaoling Xu, Yan Wang, Chunyang Bao, Jing Chen, Qiang Zhang.  (2021)  Cellulose-derived polyols as high-capacity adsorbents for rapid boron and organic pollutants removal from water.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:34214857] [10.1016/j.jhazmat.2021.126503]

7. Qihong Zhang, Wei Ren, Alexandr V. Dushkin, Weike Su.  (2020)  Preparation, characterization, in vitro and in vivo studies of olmesartan medoxomil in a ternary solid dispersion with N-methyl-D-glucamine and hydroxypropyl-β-cyclodextrin.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2020.101546]

8. Yanyun Bai, Jinxing Li, Xiumei Tai, Guoyong Wang.  (2020)  Preparation, characterization, and properties of novel meglumine-based polysiloxane surfactants.  JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,      [PMID:] [10.1016/j.jiec.2020.01.003]

9. Ming Zhao, Tianhao Li, Lichao Jia, Huilin Li, Weiyong Yuan, Chang Ming Li.  (2019)  Pristine-Graphene-Supported Nitrogen-Doped Carbon Self-Assembled from Glucaminium-Based Ionic Liquids as Metal-Free Catalyst for Oxygen Evolution.  ChemSusChem,  12  (22): (5041-5050).  [PMID:31589802] [10.1002/cssc.201901961]

10. Lei Hu, Li Gao, Xiaoming Yan, Wenji Zheng, Yan Dai, Ce Hao, Xuemei Wu, Gaohong He.  (2019)  Proton delivery through a dynamic 3D H-bond network constructed from dense hydroxyls for advanced ion-selective membranes.  Journal of Materials Chemistry A,  7  (25): (15137-15144).  [PMID:] [10.1039/C9TA04423J]

11. Jinxing Li, Yanyun Bai, Wanxu Wang, Xiumei Tai, Guoyong Wang.  (2019)  Green Glucamine-Based Trisiloxane Surfactant: Surface Activity, Aggregate Behavior, and Superspreading on Hydrophobic Surfaces.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.8b06282]

12. Xueri Nan, Jing Liu, Xiuli Wang, Xianhui Pan, Xiaomei Wang, Xu Zhang.  (2018)  Preparation of Superhydrophilic Adsorbents with 3DOM Structure by Water-Soluble Colloidal Crystal Templates for Boron Removal from Natural Seawater.  ACS Applied Materials & Interfaces,      [PMID:30289685] [10.1021/acsami.8b11763]

13. Qiang Wu, Mingyan Liu, Xiong Wang.  (2018)  A novel chitosan based adsorbent for boron separation.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2018.09.070]

14. Tianhao Li, Daomei Tang, ChangMing Li.  (2017)  A high active hydrogen evolution reaction electrocatalyst from ionic liquids-originated cobalt phosphide/carbon nanotubes.  INTERNATIONAL JOURNAL OF HYDROGEN ENERGY,      [PMID:] [10.1016/j.ijhydene.2017.07.100]

15. Xuefang Ding, Wei Wang, Yazhe Wang, Xiuli Bao, Yu Wang, Cheng Wang, Jian Chen, Fangrong Zhang, Jianping Zhou.  (2014)  Versatile Reticular Polyethylenimine Derivative-Mediated Targeted Drug and Gene Codelivery for Tumor Therapy.  MOLECULAR PHARMACEUTICS,      [PMID:25058017] [10.1021/mp5001263]

16. Xiaoling Xu, Bin Peng, Yanqiu Wang, Yaqi Dong, Hui Wang, Wentong Chen, Yan Liu, Qiang Zhang.  (2024)  Fabrication of POSS-centered polyester network as high anti-chlorine and anti-fouling separation layer of membrane via successive Photo-ATRP and interfacial polymerization for molecular separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2024.123432]

17. Guo Haikun, Li Xiang, Chai Shengchao, Li Haibin, Li Tingting, Song Shihao, Zuo Peng, Li Haolong.  (2025)  Flexible supramolecular polymer proton conductors with high mechanical-conductive decoupling ability.  Science China-Chemistry,      [PMID:] [10.1007/s11426-024-2549-6]

18. Yanzhi Dong, Gang Shu, Yibo Wei, Jinbin Pan, Dong Li, Shao-Kai Sun.  (2024)  Gram-Scale Synthesis of Renal-Clearable Tantalum Nanodots with High Water Solubility for Computed Tomography Imaging In Vivo.  ACS Nano,      [PMID:39207307] [10.1021/acsnano.4c06705]

19. Ruihao Wang, Qian Li, Xiyan Sun, Xinyu Jia, Shuxian Li, Li Wei, Xitong Sun.  (2025)  High efficiency adsorption of boron by sodium alginate/polyethyleneimine/polysiloxane composite aerogel.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39805451] [10.1016/j.ijbiomac.2025.139784]

20. Ma Li, Pan Jinbin, Shu Gang, Pan Haiyan, Li Jingang, Li Dong, Sun Shaokai.  (2024)  Non-invasive fast assessment of hepatic injury through computed tomography imaging with renal-clearable Bi-DTPA dimeglumine.  Regenerative Biomaterials,      [PMID:39398283] [10.1093/rb/rbae118]

21. Yanqin Xu, Jie Liu, Shumin Guan, Yuan Cao, Changguo Chen, Dan Wang.  (2020)  A dual pH and redox-responsive Ag/AgO/carboxymethyl chitosan composite hydrogel for controlled dual drug delivery.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,      [PMID:32614709] [10.1080/09205063.2020.1774118]

22. Lu Zhao, Li Ma, Xuetao Jia, Xiaoxue Wang, Wenjing Hou, Gang Shu, Bing Han, Dianxun Fu, Dong Li, Shao-Kai Sun, Jinbin Pan.  (2025)  Bismuth Chelate-Mediated Computed Tomography Perfusion Imaging of Acute Ischemic Stroke In Vivo.  ACS Applied Materials & Interfaces,      [PMID:40445005] [10.1021/acsami.5c02378]