MES sodium salt(MES-Na) - Ultra pure, ≥99%(T), zwitterionic buffer useful in pH range 5.5-6.7 , CAS No.71119-23-8

CAS: 71119-23-8 Cat. No.: M755528 Molecular Weight: 217.22 Beilstein Registry Number: 3765682 EC Number: 275-203-2

GRADE & PURITY Ultra pure, ≥99%(T), zwitterionic buffer useful in pH range 5.5-6.7

Storage

Room temperature

Shipped In

Normal

Overview

A zwitterionic buffer useful in the pH range of 5.5-6.5 (absorbance: <0.05 at 260 nm, 100 mM, H₂O; pK_a: 6.2 at 20°C).

A zwitterionic buffer useful in the pH range of 5.5-6.7. Has a pK_a of 6.10 at 25°C.

Absorbance (100 mM, H₂O, 260 nM):≤0.05.

Application:

• Galvanic cell without liquid junction for potentiometric determination of copper.: This study presents the use of a galvanic cell without liquid junction for the potentiometric determination of copper ions. This method can be adapted for use with MES sodium salt buffers in analytical chemistry, offering a stable and reproducible way to measure copper concentrations in various media (Migdalski et al., 2007).


• Oxygen solubilities of media used in electrochemical respiration measurements.: This research explores the oxygen solubility in various media used for electrochemical respiration measurements, which includes the use of MES sodium salt buffers. It highlights how different buffer systems affect oxygen solubility and the implications for biochemical studies involving cellular respiration (Rasmussen HN et al., 2003).

Specifications

Specifications & Purity

Ultra pure, ≥99%(T), zwitterionic buffer useful in pH range 5.5-6.7

Storage

Room temperature

Shipped In

Normal

Grade

Ultra pure

Purity

≥99%(T)

Names and Identifiers

• Canonical Smiles: C1COCCN1CCS(=O)(=O)[O-].[Na+]
• IUPAC Name: sodium;2-morpholin-4-ylethanesulfonate
• InChIKey: IRHWMYKYLWNHTL-UHFFFAOYSA-M
• INCHI: 1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1
• Isomeric SMILES: C1COCCN1CCS(=O)(=O)[O-].[Na+]
• WGK Germany: 1
• Molecular Weight: 217.22
• Beilstein: 3765682
• Reaxy-Rn: 3765682
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3765682&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Oxazinanes
      • Subclass Morpholines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Oxazinanes
• Subclass: Morpholines
• Intermediate Tree Nodes: Not available
• Direct Parent: Morpholines
• Alternative Parents: Sulfonyls Organosulfonic acids Alkanesulfonic acids Trialkylamines Oxacyclic compounds Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Morpholine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - Tertiary amine - Tertiary aliphatic amine - Dialkyl ether - Ether - Oxacycle - Azacycle - Organic alkali metal salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Organic zwitterion - Organic salt - Organic sodium salt - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as morpholines. These are organic compounds containing a morpholine moiety, which consists of a six-member aliphatic saturated ring with the formula C4H9NO, where the oxygen and nitrogen atoms lie at positions 1 and 4, respectively.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: water: 5 mg/mL
• Molecular Weight: 217.220 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 217.038 Da
• Monoisotopic Mass: 217.038 Da
• Topological Polar Surface Area: 78.100 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 219.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Sheng Chang, Qiang Yang, Jiahuan Liu, Li Yin, Jihong Han, Lanlan Zong, Xiaohui Pu.  (2024)  The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer.  MOLECULES,  29  (8): (1769).  [PMID:38675589] [10.3390/molecules29081769]

2. Fei Pan, Mu Yang, Shichuan Zhang, Wei Zhang, Yungchang Chen, Huangming Hong, Yuke Tian, Reqin Li, Huawei Weng, Zegeng Chen, Meiting Chen, Huageng Huang, Xiaoqian Li, Tongtong Feng.  (2025)  Tumor microenvironment-responsive nanoparticles composed of hyaluronic acid and stearic acid for the treatment of lung metastasis in triple-negative breast cancer.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41391799] [10.1016/j.ijbiomac.2025.149492]