Methyl propionate - analytical standard , CAS No.554-12-1

CAS: 554-12-1 Cat. No.: M110422 Molecular Weight: 88.11 Beilstein Registry Number: 1737628 EC Number: 209-060-4
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
Synonyms
METHYL PROPIONATE|Methyl propanoate|554-12-1|Propanoic acid, methyl ester|Methyl propylate|Methylpropionate|Propionic acid, methyl ester|Propionate de methyle|FEMA No. 2742|FEMA Number 2742|Propanoic acid methyl ester|PROPIONIC ACID METHYL ESTER|Methyl Pr
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1ml
M110422-1ml
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Why this grade

analytical standard Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 26 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Methyl propionate is a volatile odorant found in pineapples.

Specifications

Synonyms
METHYL PROPIONATE | Methyl propanoate | 554-12-1 | Propanoic acid, methyl ester | Methyl propylate | Methylpropionate | Propionic acid, methyl ester | Propionate de methyle | FEMA No. 2742 | FEMA Number 2742 | Propanoic acid methyl ester | PROPIONIC ACID METHYL ESTER | Methyl Pr
Specifications & Purity
analytical standard
Storage
Room temperature
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Analytical standard
Names and Identifiers
Canonical SmilesCCC(=O)OC
IUPAC Namemethyl propanoate
InChIKeyRJUFJBKOKNCXHH-UHFFFAOYSA-N
INCHI1S/C4H8O2/c1-3-4(5)6-2/h3H2,1-2H3
Isomeric SMILES CCC(=O)OC
WGK Germany 1
RTECS UF5970000
UN Number 1248
Packing Group II
Molecular Weight 88.11
Beilstein 1737628
Reaxy-Rn 1737628
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1737628&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassCarboxylic acid derivatives
Intermediate Tree Nodes Carboxylic acid esters
Direct ParentMethyl esters
Alternative Parents Monocarboxylic acids and derivatives  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Methyl ester - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as methyl esters. These are organic compounds containing a carboxyl group that is esterified with a methyl group. They have the general structure RC(=O)OR', where R=H or organyl group and R'=methyl group.
External Descriptors Wax monoesters
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
F2622539Certificate of AnalysisJun 12, 2026 M110422
L2215689Certificate of AnalysisJun 08, 2026 M110422
E1907070Certificate of AnalysisJun 08, 2026 M110422
F2217084Certificate of AnalysisDec 10, 2025 M110422
H2318039Certificate of AnalysisSep 02, 2023 M110422
Chemical and Physical Properties
SolubilitySlightly soluble in water, miscible with ethanol and ether.
SensitivityMoisture sensitive.
Refractive Index1.377
Flash Point(°F)28.4 °F - closed cup
Flash Point(°C)-2℃
Boil Point(°C)78-79°C
Melt Point(°C)-88°C
Molecular Weight88.110 g/mol
XLogP30.800
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass88.0524 Da
Monoisotopic Mass88.0524 Da
Topological Polar Surface Area26.300 Ų
Heavy Atom Count6
Formal Charge0
Complexity49.500
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Liu Yurong, Zhang Rui, Jing Hongling, Yu Daheng, Pan Renming, Chen Ruiyu.  (2023)  High-Temperature Oxidation and Hot Corrosion Behaviors and Mechanism of One Typical Aero-Engine Material 0Cr18Ni9 by One Novel Superhydrophobic and Oleophobic Ultrafine Dry Powder Extinguishing Agent.  JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE,      [PMID:] [10.1007/s11665-023-08994-z]
2. Weihao Wang, Hao Yu, Li Ma, Youquan Zhang, Yuejiao Chen, Libao Chen, Guichao Kuang, Liangjun Zhou, Weifeng Wei.  (2023)  Highly concentrated solvation structure for reversible high-voltage lithium-ion battery at low temperature.  JOURNAL OF POWER SOURCES,      [PMID:] [10.1016/j.jpowsour.2023.233849]
3. Liyang Liu, Haiying Lu, Chao Han, Xianfei Chen, Sucheng Liu, Jiakui Zhang, Xianghong Chen, Xinyi Wang, Rui Wang, Jiantie Xu, Hua Kun Liu, Shi Xue Dou, Weijie Li.  (2023)  Salt Anion Amphiphilicity-Activated Electrolyte Cosolvent Selection Strategy toward Durable Zn Metal Anode.  ACS Nano,      [PMID:37948160] [10.1021/acsnano.3c08716]
4. Jie Zhang, Wenhao Ren, Shuhui Chen, Yong Liu, Zibiao Guo, Jingchuan Dang, Wenjia Wu, Jingtao Wang.  (2023)  The Fabrication of in Situ Polymerization of 1,3-Dioxlane/Poly(vinyl alcohol)/Polyethylenimine Quasi-Solid Polymer Electrolyte for a Lithium Metal Battery Operated at Low Temperatures.  ENERGY & FUELS,      [PMID:] [10.1021/acs.energyfuels.3c02142]
5. Luming Wang, Yuhang Bian, Zhenyu Wu, Zengxi Li, Gang Wang, Chunshan Li.  (2023)  Revealing the role of hydrogen bond, mechanism and kinetic for hydroesterification of ethylene to methyl propionate.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.144331]
6. Dongyang Chen, Hongli Shen, Dongchu Chen, Nanjie Chen, Yuezhong Meng.  (2023)  Highly Soluble Dimethoxymethyl Tetrathiafulvalene with Excellent Stability for Non-Aqueous Redox Flow Batteries.  ACS Applied Materials & Interfaces,      [PMID:37341213] [10.1021/acsami.3c05387]
7. Sihao Shu, Zhongze Wang, Xing Zhang, Haonan Shi, Shangzhen Feng, Jixiang Chen.  (2023)  Efficient deoxygenation of methyl esters to hydrocarbons on Al2O3 supported Ni-Sn intermetallic compounds.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2023.113056]
8. Pengbin Lai, Boyang Huang, Xiaodie Deng, Jialin Li, Haiming Hua, Peng Zhang, Jinbao Zhao.  (2023)  A localized high concentration carboxylic ester-based electrolyte for high-voltage and low temperature lithium batteries.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.141904]
9. Miao Ma, Jidong Wang, Xiaotong Yang, Yixin Qu.  (2023)  Solubility and Thermodynamic Properties of Clotrimazole in 16 Organic Solvents at Temperature of 283.15 to 323.15 K.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/acs.jced.2c00680]
10. Yiwen Cao, Shenjie Zhu, Lin Zhang, Qun Cui, Haiyan Wang.  (2021)  Qualitative and quantitative determination of trace aldehydes and ketones in food preservative propionic acid for quality improvement.  Analytical Methods,  13  (26): (2989-2996).  [PMID:34124731] [10.1039/D1AY00742D]
11. Tingting Liu, Shui Wang, Yan Shi, Zhong Zhao.  (2021)  Solubility and Model Correlation of Doxofylline in Pure Solvents at the Temperature Range of 283.15–323.15 K.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/acs.jced.0c01088]
12. Mengmeng Liu, Shui Wang, Chao Qu, Zhichao Zhang, Yixin Qu.  (2020)  Solubility Determination and Thermodynamic Properties of Bezafibrate in Pure and Binary Mixed Solvents.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/acs.jced.0c00025]
13. Donglei Mao, Xingguang Zhang, Xiongfei Zhang, Mingmin Jia, Jianfeng Yao.  (2018)  Glucose-derived solid acids and their stability enhancement for upgrading biodiesel via esterification.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2018.07.019]
14. Bolin Li, Jie Zhou, Xin Xu, Jincheng Yu, Wei Shao, Yong Fang, Xiaolin Lu.  (2013)  Solvent quality affects chain conformational order at the polymer surface revealed by sum frequency generation vibrational spectroscopy.  POLYMER,      [PMID:] [10.1016/j.polymer.2013.02.002]
15. Jianguo Zhou, Rongjiao Zhu, Pingfang Yuan, Liqian Cao, Yiling Tian.  (2012)  Isothermal (vapour + liquid) equilibria for the binary systems of (carbon monoxide + methyl propionate) and (carbon monoxide + ethyl propionate).  JOURNAL OF CHEMICAL THERMODYNAMICS,      [PMID:] [10.1016/j.jct.2012.11.028]
16. Li Hongling, Zhu Rongjiao, Xu Wei, Xu Hongfei, Dong Zeliang, Tian Yiling.  (2009)  Vapor−Liquid Equilibrium Data of (Carbon Dioxide + Methyl Propionate) and (Carbon Dioxide + Propyl Propionate) at Pressures from (1.00 to 12.00) MPa and Temperatures from (313.0 to 373.0) K†.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/je9001784]
17. Luming Wang, Guoliang Zhang, Hui Zhao, Gang Wang, Zengxi Li, Chunshan Li.  (2024)  Encapsulation of phosphine-palladium complex in USY zeolite for hydroesterification of ethylene to methyl propionate.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2024.120976]
18. Chenxi Feng, Junyang Liu, Kai Zhao, Lei Wang, Zengxi Li, Guoliang Zhang, Chunshan Li.  (2024)  Influence of pore structure on catalytic performance of Cs-Zr/SiO2 catalyst for methyl methacrylate synthesis from methyl propionate and formaldehyde.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2024.120760]
19. Yimei Wang, Yaoyao Zhang, Xing Qiao, Shangde Sun.  (2024)  Synthesis of lipophilic antioxidant tyrosol laurate using imidazolium ionic liquid [Bmim]HSO4 as a catalyst.  FOOD CHEMISTRY,      [PMID:38237293] [10.1016/j.foodchem.2024.138418]
20. Yutao Liu, Song Gao, Wei Lü, QiXian Zhang.  (2025)  Anion Coordination Regulation with LiNO3 Additive for High-Rate Low-Temperature Lithium Metal Batteries.  ACS Applied Materials & Interfaces,      [PMID:40968669] [10.1021/acsami.5c13844]
21. Manxi Wang, Lijuan Tong, Shiwen Lv, Manxian Li, Jingyue Zhao, Xuan Li, Chuanping Li, Xiaochuan Chen, Junxiong Wu, Xiaoyan Li, Qinghua Chen, Yuming Chen.  (2025)  In Situ-Engineered MOF/Polymer Hybrid Electrolyte With 3D Continuous Ion Channels for High-Voltage and Thermal-Resistant Lithium Metal Batteries.  Interdisciplinary Materials,  (5): (763-774).  [PMID:] [10.1002/idm2.70005]
22. Weihao Wang, Qiao Luo, Liangjun Zhou, Xuanyuan Liao, Hao Yu, Li Ma, Yaowen Xu, Qingfei Meng, Yuyang Qi, Yuejiao Chen, Libao Chen, Weifeng Wei.  (2025)  Competitive ion-molecule-coordinated interactions for high-voltage and high-rate lithium batteries under ultra-wide temperature.  Science Bulletin,      [PMID:40253293] [10.1016/j.scib.2025.04.011]
23. Tingting Yan, Senlin Deng, Gang Wang, Jie Li, Wei Chang, Guoliang Zhang, Chunshan Li.  (2025)  Construction of active Cs and Zr sites for Selective production of methyl methacrylate on Cs/Zr/SiO2 catalyst.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.162915]
24. Chengcheng Wan, Zhaoru Ban, Dan Zhang, Jiumei He, Yanju Chen, Shan Tang, Qianchun Zhang.  (2025)  Highly selective detection of trace methyl sec-butyl ether using cataluminescence sensor based on mesoporous CeO2 nanoparticles.  MEASUREMENT SCIENCE and TECHNOLOGY,  36  (8): (085104).  [PMID:] [10.1088/1361-6501/adf24a]
25. Junping Zhang, Songsong Chen, Shasha Cao, Chunshan Li, Hui Zhao, Xiangping Zhang, Chaohe Yang.  (2025)  Isobaric vapor–liquid equilibrium for the binary system of methyl propionate and methyl methacrylate at 90.0, 75.0, 60.0, 45.0 and 30.0 kPa.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2025.09.019]
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