Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 17 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Methylothiazolinone is a bacterial and fungal inhibitor and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases ( MMPs ) in human bronchial epithelial cells to induce apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels.
| Isomeric SMILES | CN1C(=O)C=CS1 |
|---|---|
| WGK Germany | 3 |
| RTECS | NX8157080 |
| UN Number | 3261 |
| Molecular Weight | 115.15 |
| Beilstein | 606203 |
| Reaxy-Rn | 606203 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=606203&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Min Chen, Xin Zhang, Jiuhui Qu. (2025) Unveiling Scale-Design Principle at Electrical Confinement Materials for Water Purification. ADVANCED MATERIALS, [PMID:40801167] [10.1002/adma.202508494] |
| 2. Jingwei Wang, Jiaxin Wang, Pan Zhao, Shuzhen Li, Xuwang Zhang, Dan Xu, Qiao Ma. (2025) Deciphering the enzymatic responses, composition, network complexity, and functional degraders of the marine sediment bacterial community in response to 2-methyl-4-isothiazoline-3-one exposure. MARINE ENVIRONMENTAL RESEARCH, [PMID:40850239] [10.1016/j.marenvres.2025.107469] |
| 3. Liping Wei, Kexin Zhou, Qian Rao, Hui-qiang Li, Ping Yang. (2023) Introducing MXenes into the Heterogeneous Catalyst: Synthesizing Mo2CTx@Fe3O4 with Excellent Recoverability to Degrade Methylisothiazolinone in the Electro-Fenton System. ENVIRONMENTAL ENGINEERING SCIENCE, [PMID:] [10.1089/ees.2023.0078] |
| 4. Zhizhuo Chai, Jingquan Wang, Yixue Dai, Erdeng Du, Hongguang Guo. (2023) Synergy between UV light and trichloroisocyanuric acid on methylisothiazolinone degradation: Performance, kinetics and degradation pathway.. ENVIRONMENTAL RESEARCH, [PMID:37481058] [10.1016/j.envres.2023.116693] |
| 5. Peifu Sun, Xiao Zhang, Zhiren Guo, Xinyue Liu, Yuanming Lan, Dongxiang Zhang, Hansheng Li, Jinying Li, Helei Liu, Xiyan Xu. (2023) An adsorptive photo-Fenton-like removal of 1,2-benzisothiazolin-3-one by NH2-MIL-53(Fe) under simulated solar light. NEW JOURNAL OF CHEMISTRY, 47 (17): (8334-8346). [PMID:] [10.1039/D3NJ00771E] |
| 6. Wei Tian, Shunli Wang, Zhiling Guo, Haitao Yu, Limei Tian. (2023) Antifouling and anticorrosion function of repeatable self-healing polyurethane composite inspired by the self-healing principle of cartilage tissue. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.142346] |
| 7. Shuang Pan, Chang Liu, Yanchao Li, Can Wang, Xiaoya Cui, Ning Liu, Cong Zhang, Israel Hakizimana, Xin Zhao, Weidi Liu, Yanan Chen. (2022) Ultrafast self-assembly Fe2O3 nanoparticles confined in carbon layers toward robust heterogeneous electro-Fenton reaction. ELECTROCHIMICA ACTA, [PMID:] [10.1016/j.electacta.2022.141262] |
| 8. Wan-Jun Long, Hai-Long Wu, Tong Wang, Ming-Yue Dong, Ru-Qin Yu. (2020) Interference-free analysis of multi-class preservatives in cosmetic products using alternating trilinear decomposition modeling of liquid chromatography diode array detection data. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2020.105847] |
| 9. Dong Yuhao, Li Shougang, Zhao Dan, Liu Jin, Ma Shuiyan, Geng Jinzhu, Lu Chengping, Liu Yongjie. (2020) IolR, a negative regulator of the myo-inositol metabolic pathway, inhibits cell autoaggregation and biofilm formation by downregulating RpmA in Aeromonas hydrophila. npj Biofilms and Microbiomes, 6 (1): (1-12). [PMID:32433466] [10.1038/s41522-020-0132-3] |
| 10. Xiao-Li Yin, Hui-Wen Gu, Ali R. Jalalvand, Ya-Juan Liu, Ying Chen, Tian-Qin Peng. (2018) Dealing with overlapped and unaligned chromatographic peaks by second-order multivariate calibration for complex sample analysis: Fast and green quantification of eight selected preservatives in facial masks. JOURNAL OF CHROMATOGRAPHY A, [PMID:30243735] [10.1016/j.chroma.2018.09.019] |
| 11. Pengfei Yu, Zhongyu Guo, Jieqiong Wang, Yuchen Guo, Tingting Wang, Lilan Zhang. (2024) Insight into the photodegradation of methylisothiazolinone and benzoisothiazolinone in aquatic environments. WATER RESEARCH, [PMID:39173356] [10.1016/j.watres.2024.122301] |
| 12. Zhenzhao Wang, Lili Liu, Zhen Li, Linna Li, Xingtong Liu, Rikun Cui, Fujun Yao, Lei Tian, Xiaofeng Kang, YanLi Guo. (2024) Nanopore-based single-molecule investigation of the effects of anthracycline anticancer drugs on i-motif. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112623] |
| 13. Shifang Yang, Zexuan Zhang, Qianpeng Hou, Yunpeng Liu, Chi Gong. (2024) Preparation, characterisation and enhanced fungistatic properties of silicone rubber with different concentrations of CMIT/MIT. High Voltage, [PMID:] [10.1049/hve2.12473] |
| 14. Rao Qian, Li Hui-qiang, Yang Ping, Guo Ziou. (2025) Synthesis of Mo2C@CeO2@Fe3O4 particles for enhancing three-dimensional heterogeneous electro-Fenton degradation of MIT and HEDP. KOREAN JOURNAL OF CHEMICAL ENGINEERING, [PMID:] [10.1007/s11814-025-00386-4] |
| 15. Hui-qiang Li, Mei-yu Zhang, Ke-xin Zhou, Ping Yang, Zhi-wei Gan, Zhi Li. (2025) Degradation of HEDP and MIT in a heterogeneous electro-Fenton-like system using cobalt-based bimetallic catalysts. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2025.138469] |
| 16. Minglin Wang, Ye Li, Kun Yang, Rui Liu, Mengqi Wang, Kongyin Zhao. (2025) Dried MoS2–Cobalt Alginate Membrane for Rapid Catalytic Degradation of Methylisothiazolinone. Gels, 11 (11): (852). [PMID:41294537] [10.3390/gels11110852] |
| 17. Lihong Wang, Jialu Liu, Heyao Zhang, Fan Zhang, Yongze Liu, Tao Zhang. (2026) Removal of high-risk organic recalcitrants in reverse osmosis concentrate by solar/ZnO: performance, mechanism, and application. Journal of Cleaner Production, [PMID:] [10.1016/j.jclepro.2026.147989] |
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