Methylthiouracil - 10mM in DMSO , CAS No.56-04-2

CAS: 56-04-2 Cat. No.: M408545 Summenformel: C₅H₆N₂OS Molekulargewicht: 142.18 EG-Nummer: 200-252-3

QUALITÄT & REINHEIT 10mM in DMSO

Synonyms

NSC-193526, NSC-9378 | 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

Methylthiouracil (NSC-193526, NSC-9378) is an antithyroid agent. Methylthiouracil suppresses the productionTNF-αandIL-6, and the activation ofNF-κBandERK1/2.
In vitro

Methylthiouracil acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. Methylthiouracil is also used in combination with radioactive iodine.

In vivo

Cell Data

cell lines：MM1.S, MM.1R, LR5, RPMI 8226, DOX40, OPM1, OPM2, INA6, and U266

Concentrations：

Incubation Time：

Powder Purity:≥99%

Spezifikationen

Synonyme

NSC-193526, NSC-9378 | 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

Methylthiouracil (NSC-193526, NSC-9378) is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Namen und Kennungen

Isomere SMILES

CC1=CC(=O)NC(=S)N1

UN-Nummer

3077

Verpackungsgruppe

III

Molekulargewicht

142.18

Reaxy-Rn

115648

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=115648&ln=

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 64 mg/mL (199.17 mM); Water: Insoluble; Ethanol: Insoluble
• Schmelzpunkt (°C): 330°C