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MK-8189 - ≥99% , CAS No.1424371-93-6
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
MK-8189 is a potent, orally active and selective PDE10A inhibitor with a K i value of 29 pM. MK-8189 can be used in research of schizophrenia
In Vivo
MK-8189 (0.25-0.75 mg/kg; po) attenuates rats' locomotor activity in a dose-dependent manner . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wistar-Hannover rats Dosage: 0.25, 0.5, and 0.75 mg/kg Administration: Oral administration Result: Improved identification ability relative to the vector handling animal.
Form:Solid
IC50& Target:PDE10A 29 pM (Ki)
Specifications
Specifications & Purity
≥99%
Biochemical and Physiological Mechanisms
MK-8189 is a potent, orally active and selective PDE10A inhibitor with a K i value of 29 pM. MK-8189 can be used in research of schizophrenia.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥99%
Names and Identifiers
| Molecular Weight | 382.48 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMSO : 125 mg/mL (326.81 mM; Need ultrasonic) |
|---|
Solution Calculators
Reviews
Customer Reviews
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