ML161 (Parmodulin 2) - 10mM in DMSO , CAS No.423735-93-7

CAS: 423735-93-7 Cat. No.: M408640 Summenformel: C₁₇H₁₇BrN₂O₂ Molekulargewicht: 361.23 EG-Nummer: 803-969-5

GRADE & PURITY 10mM in DMSO

Synonyms

Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

ML161 (Parmodulin 2) ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.
In vitro

ML-161 is an allosteric inhibitor of PAR1. ML-161 displays dose-dependent inhibition of thrombin-induced platelet activation, as measured by P-selectin expression. ML-161 displays selective inhibition of SFLLRN and thrombin-induced platelet aggregation, both of which operate via PAR1, and has no effect on AYPGKF, thromboxane, or ADP-induced platelet aggregation, which are all agonists at alternative platelet GPCRs.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyme

Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

ML161 (Parmodulin 2) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

• Isomere SMILES: CCCC(=O)NC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2Br
• WGK Deutschland: 3
• Molekulargewicht: 361.23
• Reaxy-Rn: 22413221
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22413221&ln=

Häufig gestellte Fragen

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 423735-93-7, the molecular formula is C17H17BrN2O2, and the molecular weight is 361.23 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.