Molindone Hydrochloride - 10mM in DMSO , Serotonin 2a (5-HT2a) receptor antagonist, CAS No.15622-65-8, Serotonin 2a (5-HT2a) receptor antagonist

CAS: 15622-65-8 Cat. No.: M421865 Summenformel: C₁₆H₂₄N₂O₂·HCl Molekulargewicht: 312.84 EG-Nummer: 633-875-8

GRADE & PURITY 10mM in DMSO

Synonyms

3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one hydrochloride | Lidone | Moban | MOLINDONE HYDROCHLORIDE [MART.] | DTXCID3025417 | MLS001333061 | Molindone hydrochloride | 3-Ethyl-2-Methyl-5-(4-Morpholin-4-Iumylmethyl)-1,5,6,7-T

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Molindone hydrochloride is the hydrochloride salt form of molindone, a conventional antipsychotic used in the therapy of schizophrenia. It is a dopamine D2/D5 receptor antagonist.

Specifications

Synonyme

3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one hydrochloride | Lidone | Moban | MOLINDONE HYDROCHLORIDE [MART.] | DTXCID3025417 | MLS001333061 | Molindone hydrochloride | 3-Ethyl-2-Methyl-5-(4-Morpholin-4-Iumylmethyl)-1,5,6,7-T

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

D2 dopamine receptor antagonist; MAO inhibitor.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

ANTAGONIST

Mechanismus der Wirkung

Serotonin 2a (5-HT2a) receptor antagonist

Namen und Kennungen

• Pubchem Sid: 528773780
• Kanonisches Lächeln: CCC1=C(NC2=C1C(=O)C(CC2)CN3CCOCC3)C.Cl
• IUPAC Name: 3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one;hydrochloride
• InChIKey: GQWNECFJGBQMBO-UHFFFAOYSA-N
• INCHI: 1S/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H
• Isomere SMILES: CCC1=C(NC2=C1C(=O)C(CC2)CN3CCOCC3)C.Cl
• WGK Deutschland: 3
• RTECS: NM3325000
• Molekulargewicht: 312.84
• Reaxy-Rn: 5182754
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5182754&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Indoles and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Indoles and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Indoles and derivatives
• Alternative Parents: Aryl alkyl ketones Aralkylamines Substituted pyrroles Morpholines Vinylogous amides Heteroaromatic compounds Trialkylamines Oxacyclic compounds Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organic zwitterions Organic oxides Organic chloride salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Indole or derivatives - Aryl ketone - Aryl alkyl ketone - Aralkylamine - Substituted pyrrole - Oxazinane - Morpholine - Vinylogous amide - Pyrrole - Heteroaromatic compound - Tertiary aliphatic amine - Ketone - Tertiary amine - Azacycle - Ether - Dialkyl ether - Oxacycle - Amine - Organic zwitterion - Organic salt - Organic chloride salt - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as indoles and derivatives. These are organic compounds containing an indole, which is a bicyclic ring system made up of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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LMNA Tbio Prelamin-A/C (36751 Activities)

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BLM Tchem Bloom syndrome protein (4248 Activities)

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MPHOSPH8 Tbio M-phase phosphoprotein 8 (656 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Cryptococcus neoformans (21258 Activities)

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Candida albicans (78123 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

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Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Molekulargewicht: 312.830 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 312.16 Da
• Monoisotopic Mass: 312.16 Da
• Topological Polar Surface Area: 45.300 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 354.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3