Monobenzone - Moligand™, 10mM in DMSO , Tyrosinase inhibitor, CAS No.103-16-2, Tyrosinase inhibitor

CAS: 103-16-2 Cat. No.: M408651 Summenformel: C₁₃H₁₂O₂ Molekulargewicht: 200.23 Beilstein Registry Number: 1958305 EG-Nummer: 203-083-3

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

4-​(phenylmethoxy)​-phenol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

Monobenzone Monobenzone is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase .
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyme

4-​(phenylmethoxy)​-phenol

Spezifikationen & Reinheit

Moligand™, 10mM in DMSO

Biochemische und physiologische Mechanismen

Monobenzone is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

INHIBITOR

Mechanismus der Wirkung

Tyrosinase inhibitor

Produkteigenschaften

• ALogP: 3.4

Namen und Kennungen

• Isomere SMILES: C1=CC=C(C=C1)COC2=CC=C(C=C2)O
• WGK Deutschland: 2
• RTECS: SJ7700000
• UN-Nummer: 2430
• Molekulargewicht: 200.23
• Beilstein: 1958305
• Reaxy-Rn: 1958305
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1958305&ln=

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 100 mg/mL (114.53 mM); Ethanol: -1 mg/mL
• Schmelzpunkt (°C): 117-122°C

Referenzen

1. Chen Hong, Yifan Zhang, Lili Yang, Haoyang Xu, Kang Cheng, Zhi Lv, Kaixian Chen, Yiming Li, Huali Wu.  (2023)  Epimedin B exhibits pigmentation by increasing tyrosinase family proteins expression, activity, and stability.  Journal of Pharmaceutical Analysis,      [PMID:38352950] [10.1016/j.jpha.2023.09.006]

2. Hong Chen, Yang Lili, Zhang Yifan, Li Yiming, Wu Huali.  (2022)  Epimedium brevicornum Maxim. Extract exhibits pigmentation by melanin biosynthesis and melanosome biogenesis/transfer.  Frontiers in Pharmacology,      [PMID:36249817] [10.3389/fphar.2022.963160]

3. Jia-Pei Guo, Fang-Jing Liu, Lei-Lei Bie, Xing-Gang Si, Yan-Hong Li, Ping Song, Nian Liu, Yun-Peng Zhao, Zai-Xing Huang, Jing-Pei Cao, Xian-Yong Wei.  (2022)  Selective cleavage of C–O bond in lignin and lignin model compounds over iron/nitrogen co-doped carbon supported Ni catalyst.  FUEL,      [PMID:] [10.1016/j.fuel.2022.123338]

4. Rongrong Li, Wei Wang, Xianlang Chen, Hong Chen, Huanhuan Bao, Yuwei Zhu, Jia Zhao, Deman Han.  (2020)  Equilibrium Solubility Determination and Correlation of Monobenzone in Fifteen Monosolvents at a Series of Temperatures.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/acs.jced.9b00817]

5. Ying Kang, Xingmei Lu, Guangjin Zhang, Xiaoqian Yao, Jiayu Xin, Shaoqi Yang, Yongqing Yang, Junli Xu, Mi Feng, Suojiang Zhang.  (2019)  Metal-Free Photochemical Degradation of Lignin-Derived Aryl Ethers and Lignin by Autologous Radicals through Ionic Liquid Induction.  ChemSusChem,  12  (17): (4005-4013).  [PMID:31291505] [10.1002/cssc.201901796]

6. Feng Chen, Xuebin Lin, Wei Chen, Na Wen, Yanqiao Jin.  (2024)  Double core–shell hollow nanocage CuO@Co3O4 for the selective hydrogenolysis of C–O bonds of lignin without external hydrogen.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.152002]

7. Zifan Wu, Yacong Deng, Fengyu Tian, Yidi Wang, Na Fan, Guangzheng Sun, Yichuan Li, Yuan Pan, Bin Liu, Bin Dong, Han Hu, Yongming Chai.  (2025)  N-doped biochar supported Ni-Co alloy catalyst for efficient hydrocracking of enzymatic hydrolysis lignin to monophenols in water.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.159424]

8. Lin Hu, Jingcheng Wu, Xian-Yong Wei, Changlin Yu, Lei Li, Lingling Li.  (2024)  Reaction synergy of RuFe bimetallic catalysts on mordenite in lignin hydrogenolysis for aromatic compounds production.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.130643]

9. Feng Chen, Xiang Xia, Wei Chen, Wei Liu, Xinxin Liao, Lei Xiong, Yanqiao Jin.  (2026)  Highly efficient sea urchin-like N-doped CuCo bimetallic catalyst for selective cleavage of α-O-4 linkage in lignin.  Journal of Environmental Chemical Engineering,  14  (3): (122374).  [PMID:] [10.1016/j.jece.2026.122374]