Motol - AR, ≥99% , CAS No.55-55-0

CAS: 55-55-0 Cat. No.: M110716 Molecular Weight: 172.19 Beilstein Registry Number: 3919382 EC Number: 200-237-1 PubChem CID: 5930

GRADE & PURITY AR, ≥99%

Synonyms

Genol | 4-(Methylamino)phenol hemisulfate salt | p-Methylaminophenol sulphate (2:1) | Metatyl | Graphol | N-Methyl-p-aminophenol sulfate | CHEBI:55413 | Paramethylaminophenol sulfate | p-Methylaminophenolsulfate | Planetol | 4-(Methylamino)phenol hemisulf

Storage

Protected from light,Room temperature,Argon charged,Cool

Shipped In

Normal

Overview

Metol (4-methylaminophenol sulphate) is white crystalline which helps in determination of phosphate by reduction reaction of phosphomolybdic acid to molybdenum blue with intense colour. It is used as reducing agent. A solution of Metol could be prepared by dissolving a known amount in water with hydrated sodium sulphite along with which few drops of Brij needs to be added.

Specifications

Synonyms

Genol | 4-(Methylamino)phenol hemisulfate salt | p-Methylaminophenol sulphate (2:1) | Metatyl | Graphol | N-Methyl-p-aminophenol sulfate | CHEBI:55413 | Paramethylaminophenol sulfate | p-Methylaminophenolsulfate | Planetol | 4-(Methylamino)phenol hemisulf

Specifications & Purity

AR, ≥99%

Storage

Protected from light, Room temperature, Argon charged, Cool

Shipped In

Normal

Grade

AR

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 488179963
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488179963
• Isomeric SMILES: CNC1=CC=C(C=C1)O.CNC1=CC=C(C=C1)O.OS(=O)(=O)O
• WGK Germany: 3
• RTECS: SL8650000
• PubChem CID: 5930
• UN Number: 3077(international)
• Packing Group: III
• Molecular Weight: 172.19
• Beilstein: 3919382
• Reaxy-Rn: 3919382

Associated Targets(Human)

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

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NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

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CXCL8 Tchem Interleukin-8 (642 Activities)

Discover Target: CXCL8

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GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

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NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

Discover Target: NR1H4

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CASP1 Tchem Caspase-1 (6235 Activities)

Discover Target: CASP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

Discover Target: ALOX15

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

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Lymphoblastoid cell (5959 Activities)

Explore this target

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HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)

Discover Target: HIF1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

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RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)

Discover Target: RECQL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

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Associated Targets(non-human)

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)

Discover Target: Ppard

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lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Impa1 Inositol monophosphatase 1 (16203 Activities)

Discover Target: Impa1

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Mechanisms of Action

Chemical and Physical Properties

• Solubility: It is soluble in water (50 mg/mL).
• Sensitivity: Light & Air Sensitive.
• Flash Point(°F): 210.2 °F
• Flash Point(°C): 99 °C
• Melt Point(°C): 259-260°C
• Molecular Weight: 344.390 g/mol
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 2
• Exact Mass: 344.104 Da
• Monoisotopic Mass: 344.104 Da
• Topological Polar Surface Area: 148.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 158.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Xiaoxian Hu, Jing Qian, Juan Yang, Xiaomin Hu, Yanjiao Zou, Nianjun Yang.  (2023)  Construction of Ce-MOF@COF hybrid nanostructure with controllable thickness for the electrochemical sensitive detection of metol.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,      [PMID:] [10.1016/j.jelechem.2023.117756]

2. Jianxia Qi, Wanting Zhou, Chengyuan Yang, Wen Liu, Chang Guan, Chengyun Zhang, Qingyan Han, Wei Gao, Lipeng Zhu, Jun Dong.  (2024)  Fabrication of sandwich nanostructured substrates with Au@Ag NCs/Graphene/AgMP for ultrasensitive SERS detection.  MATERIALS RESEARCH BULLETIN,      [PMID:] [10.1016/j.materresbull.2024.113107]

3. Zhou Langjun, Peng Yi, Hu Yuling, Li Gongke.  (2017)  In Situ Growth of Flexible Polyphenylene-Conjugated Microporous Polymer Films for Fluorescence Detection of the Total Quantity of Developing Agents and Their Oxidation Products.  Journal of Analysis and Testing,  1  (1): (1-7).  [PMID:] [10.1007/s41664-017-0006-8]

4. Dongdong Zhu, Su Mei Liu, Aude Leynaert, Paul Tréguer, Morgane Gallinari, Heting Zhou, Jill N. Sutton.  (2025)  A wet chemical extraction protocol for measuring biogenic silica in sediments of marginal seas and open ocean.  MethodsX,      [PMID:41340935] [10.1016/j.mex.2025.103723]