MPH-220 , CAS No.2649776-79-2

CAS: 2649776-79-2 Cat. No.: M647601 Summenformel: C₂₀H₂₁N₃O₃S Molekulargewicht: 383.46

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness.

In Vitro

MPH-220 (0-50 µM) inhibits Actin-activated ATPase activity in human muscle myosin samples. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

MPH-220 (25-30 mg/kg, i.p. or oral gavage) reduces skeletal muscle force without cardiovascular effects in anesthetized rats . MPH-220 (15 mg/kg, oral administration) improves gait functions in rats with brain injury . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Anesthetized rats Dosage: 25-30 mg/kg Administration: Intraperitoneal injection (i.p.) or oral gavage Result: Reduced skeletal muscle force. Observed MPH-220 distribution in rat tissues in a time-dependent manner and a dose-dependent, few-fold accumulation in skeletal muscle.

Specifications

Biochemische und physiologische Mechanismen

MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2 . MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

• Molekulargewicht: 383.46