N,N-Dibutylethanolamine - ≥99% , CAS No.102-81-8

CAS: 102-81-8 Cat. No.: N164464 Molecular Weight: 173.3 Beilstein Registry Number: 1738441 EC Number: 203-057-1
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
EINECS 203-057-1 | N-(2-HYDROXYETHYL)DIBUTYLAMINE | N,N-Dibutyl-2-hydroxyethylamine | NCGC00091656-01 | 2-(dibutylamino) ethanol | Q20963640 | SMR001371991 | MLS002454367 | N,N-Dibutyl-N-(2-hydroxyethyl)amine | Tox21_200702 | dibutyl ethanolamine | NCGC00
Storage
Room temperature
Shipped In
FedEx DG Service
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25ml
N164464-25ml
8
$9.90
100ml
N164464-100ml
10
$19.90
500ml
N164464-500ml
2
$40.90
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2-(Dibutylamino)ethanol is a tertiary amine.
2-(Dibutylamino)ethanol (DBAE) may be used as a coreactant to enhance the electrochemiluminescence (ECL) of tris(2,2′-bipyridyl)ruthenium(II) [Ru(bpy)32+], employed in the ECL immunoassays and DNA probe assays. DBAE may also be used as a catalyst during the synthesis of protected D-erythro-(2S,3R)-sphingosine.

Specifications

Synonyms
EINECS 203-057-1 | N-(2-HYDROXYETHYL)DIBUTYLAMINE | N, N-Dibutyl-2-hydroxyethylamine | NCGC00091656-01 | 2-(dibutylamino) ethanol | Q20963640 | SMR001371991 | MLS002454367 | N, N-Dibutyl-N-(2-hydroxyethyl)amine | Tox21_200702 | dibutyl ethanolamine | NCGC00
Specifications & Purity
≥99%
Storage
Room temperature
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
Pubchem Sid488180506
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180506
Canonical SmilesCCCCN(CCCC)CCO
IUPAC Name2-(dibutylamino)ethanol
InChIKeyIWSZDQRGNFLMJS-UHFFFAOYSA-N
INCHI1S/C10H23NO/c1-3-5-7-11(9-10-12)8-6-4-2/h12H,3-10H2,1-2H3
Isomeric SMILES CCCCN(CCCC)CCO
WGK Germany 1
RTECS KK3850000
UN Number 2873
Packing Group III
Molecular Weight 173.3
Beilstein 1738441
Reaxy-Rn 1738441
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1738441&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic nitrogen compounds
ClassOrganonitrogen compounds
SubclassAmines
Intermediate Tree Nodes Alkanolamines
Direct Parent1,2-aminoalcohols
Alternative Parents Trialkylamines  Primary alcohols  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAliphatic acyclic compounds
Substituents Tertiary aliphatic amine - Tertiary amine - 1,2-aminoalcohol - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

29 results found

Lot NumberCertificate TypeDateItem
K2024195Certificate of AnalysisJun 11, 2026 N164464
G2328036Certificate of AnalysisMay 19, 2026 N164464
G2328027Certificate of AnalysisMay 19, 2026 N164464
I2002004Certificate of AnalysisMar 20, 2026 N164464
G2017003Certificate of AnalysisFeb 05, 2026 N164464
G2017004Certificate of AnalysisFeb 05, 2026 N164464
B2301259Certificate of AnalysisNov 05, 2025 N164464
B2301258Certificate of AnalysisNov 05, 2025 N164464
G2215013Certificate of AnalysisApr 07, 2025 N164464
G2215012Certificate of AnalysisApr 07, 2025 N164464
G2215011Certificate of AnalysisApr 07, 2025 N164464
K2401444Certificate of AnalysisOct 28, 2024 N164464
E2126275Certificate of AnalysisMar 20, 2024 N164464
E2126274Certificate of AnalysisMar 20, 2024 N164464
C2115178Certificate of AnalysisDec 19, 2023 N164464
C2115179Certificate of AnalysisDec 19, 2023 N164464
F2512170Certificate of AnalysisAug 30, 2023 N164464
C2412364Certificate of AnalysisAug 30, 2023 N164464
C2412365Certificate of AnalysisAug 30, 2023 N164464
H2331008Certificate of AnalysisAug 30, 2023 N164464
C2412356Certificate of AnalysisAug 30, 2023 N164464
C2412362Certificate of AnalysisAug 30, 2023 N164464
C2412363Certificate of AnalysisAug 30, 2023 N164464
G2017005Certificate of AnalysisMay 09, 2023 N164464
D2327153Certificate of AnalysisApr 23, 2023 N164464
G2215015Certificate of AnalysisJun 21, 2022 N164464
G2215014Certificate of AnalysisJun 21, 2022 N164464
K2313015Certificate of AnalysisMay 28, 2021 N164464
E2326274Certificate of AnalysisMay 28, 2021 N164464

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Chemical and Physical Properties
SolubilitySolubility in water: Practically insoluble
Refractive Index1.44
Flash Point(°F)203 °F
Flash Point(°C)90 °C
Boil Point(°C)229-230 °C(lit.)
Melt Point(°C)-70 °C
Molecular Weight173.300 g/mol
XLogP32.100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count8
Exact Mass173.178 Da
Monoisotopic Mass173.178 Da
Topological Polar Surface Area23.500 Ų
Heavy Atom Count12
Formal Charge0
Complexity77.900
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Yitian Huang, Dandan Zhao, Yanjie Chen, Shupei Zhang, Feng Lin, Hong Dai.  (2022)  Ratiometric electrochemiluminescence biosensor for hepatitis C virus E2 protein based on block copolymers-solubilized Ir(ppy)3 with high electrochemiluminescence efficiency.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2022.141028]
2. Xianda Han, Zhigang Yu, Yangkejia Xiang, Fengqin Li, Xiaoping Tan, Lan Xu, Guiling Zhang.  (2022)  Electrochemical fabrication of Ru[bpy]32+@Cu-MOF(-SH)/Au photo/electrochemical coupling interface and its DNA-based biosensing performance.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2022.153697]
3. Tingting Han, Jinling Yang, Yan Wang, Yue Cao, Yuanyuan Wang, Hong-Yuan Chen, Jun-Jie Zhu.  (2021)  Boosted anodic electrochemiluminescence from blue-emissive sulfur quantum dots and its bioanalysis of glutathione.  ELECTROCHIMICA ACTA,      [PMID:] [10.1016/j.electacta.2021.138281]
4. Yue Lin, Jinpeng Jia, Rui Yang, Daozhen Chen, Jian Wang, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin.  (2019)  Ratiometric Immunosensor for GP73 Detection Based on the Ratios of Electrochemiluminescence and Electrochemical Signal Using DNA Tetrahedral Nanostructure as the Carrier of Stable Reference Signal.  ANALYTICAL CHEMISTRY,      [PMID:30742421] [10.1021/acs.analchem.9b00013]
5. Dandan Fang, Mian Pan, Huan Yi, Hong Dai, Zhensheng Hong, Xiangqin Zheng, Yanyu Lin.  (2019)  Enhanced electrochemiluminescence of luminol-DBAE system based on self-assembled mesocrystalline hybrid for the detection of ovarian cancer marker.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2019.01.151]
6. Jialian Ding, Bin Su.  (2024)  Dual-Coreactants Enhanced Electrochemiluminescence.  CHEMISTRY-A EUROPEAN JOURNAL,      [PMID:39560166] [10.1002/chem.202403804]
7. Zhigang Yu, Yangkejia Xiang, Xianda Han, Yi Guang, Fengqin Li.  (2024)  Study on the photo/electrochemical bi-functional properties of a coupling interface of Ru[dcbpy]32+-AMT/Au by SECM imaging-based joint analytical method.  TALANTA,      [PMID:38897005] [10.1016/j.talanta.2024.126423]
8. Qian Qu, Yan Hu, Jiahao Xiong, Yu Ding, Yuqi Tang, Lingrui Chen, Yajun Zhao, Yuanzhu Mi.  (2024)  Two-step synthesis of ionic liquid demulsifiers for demulsification of water-in-oil emulsion.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.130210]
9. Li Fu, Pengjie Dong, Zerui Liu, Qi Li, Yingshu Guo.  (2024)  Unary Au Nanocrystal with Prestored Electrons and Intrinsic Low Hole-Injected Potential for Low-Triggering Potential Electrochemiluminescence.  ANALYTICAL CHEMISTRY,      [PMID:39480793] [10.1021/acs.analchem.4c04594]
10. Qinghai Long, Yutao Bai, Anteng Dai, Huajie Qiu, Xuanang Fu, Xiaoyun Chen, Chao Liu, Waseem Hayat, Bihong Lv, Guohua Jing, Zuoming Zhou.  (2025)  Energy-efficient CO₂ capture using a biphasic tertiary-amine ionic liquid with reversible phase behavior.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.167326]
11. Jian-Dong Wang, Qi Gu, Zi-Hui Cai, Guo-Sheng Liu, Quan Zhou, Li-Na Fu, Shi-Liang Yang, Su Zhang, Yujie Fu.  (2023)  Efficient Extraction and Mechanism Analysis of Different Polarity Phytochemicals from Rosa roxburghii by a Green CO2-Responsive Switchable Solvent Combined with Ultrasound.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.3c06085]
12. Jielong Zhou, Bo Wang, Xiandong Hao, Zhiyong Xu, Wenbo Zhao.  (2025)  A systematic mathematical model to accurately predict SO2 absorption performance of binary mixture of alkanolamine and ionic liquid.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.133087]
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