N3-C5-NHS ester - ≥98% , CAS No.866363-70-4

CAS: 866363-70-4 Cat. No.: N651731 Summenformel: C₁₀H₁₄N₄O₄ Molekulargewicht: 254.25 PubChem CID: 11594035

GRADE & PURITY ≥98%

Synonyms

1-[(6-Azidohexanoyl)oxy]pyrrolidine-2,5-dione | FVWGCTQOFSJEDB-UHFFFAOYSA-N | PD125930 | 6-azido-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester | DTXSID10469149 | Hexanoic acid, 6-azido-, 2,5-dioxo-1-pyrrolidinyl ester | BP-25454 | A1-06739 | HY-126523 | 2

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Form:Liquid

IC50& Target:Non-cleavable

Specifications

Synonyme

1-[(6-Azidohexanoyl)oxy]pyrrolidine-2,5-dione | FVWGCTQOFSJEDB-UHFFFAOYSA-N | PD125930 | 6-azido-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester | DTXSID10469149 | Hexanoic acid, 6-azido-, 2,5-dioxo-1-pyrrolidinyl ester | BP-25454 | A1-06739 | HY-126523 | 2

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥98%

Namen und Kennungen

• Kanonisches Lächeln: C1CC(=O)N(C1=O)OC(=O)CCCCCN=[N+]=[N-]
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 6-azidohexanoate
• InChIKey: FVWGCTQOFSJEDB-UHFFFAOYSA-N
• INCHI: 1S/C10H14N4O4/c11-13-12-7-3-1-2-4-10(17)18-14-8(15)5-6-9(14)16/h1-7H2
• Isomere SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCCN=[N+]=[N-]
• PubChem CID: 11594035
• Molekulargewicht: 254.25

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrrolidine-2-ones
• Alternative Parents: Dicarboximides Lactams Azo imides Azo compounds Monocarboxylic acids and derivatives Azacyclic compounds Organic zwitterions Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-pyrrolidone - Dicarboximide - Azo compound - Azo imide - Lactam - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Azacycle - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Organic zwitterion - Organic salt - Aliphatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 100 mg/mL (393.33 mM; Need ultrasonic)
• Molekulargewicht: 254.240 g/mol
• XLogP3: 1.100
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 254.102 Da
• Monoisotopic Mass: 254.102 Da
• Topological Polar Surface Area: 78.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 373.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1