NCT02 - Moligand™, ≥99% , CAS No.790245-61-3

CAS: 790245-61-3 Cat. No.: N648209 Summenformel: C₁₇H₁₆N₂O₂S Molekulargewicht: 312.39 EG-Nummer: 840-752-4 PubChem CID: 2501755

QUALITÄT & REINHEIT Moligand™, ≥99%

Synonyms

2-(6,7-Dihydro-5H-indeno[5,6-b]furan-3-yl)-N-(5-methylthiazol-2-yl)acetamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

NCT02 is a cyclin K degrader. NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12. NCT02 has the potential for the research of metastatic colorectal cancer (CRC).

Form:Solid

Spezifikationen

Synonyme

2-(6,7-Dihydro-5H-indeno[5,6-b]furan-3-yl)-N-(5-methylthiazol-2-yl)acetamide

Spezifikationen & Reinheit

Moligand™, ≥99%

Biochemische und physiologische Mechanismen

NCT02 is a cyclin K degrader. NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12 . NCT02 has the potential for the research of metastatic colorectal cancer (CRC).

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Reinheit

≥99%

Namen und Kennungen

Isomere SMILES

CC1=CN=C(S1)NC(=O)CC2=COC3=C2C=C4CCCC4=C3

PubChem CID

2501755

Molekulargewicht

312.39

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 50 mg/mL (160.06 mM; Need ultrasonic)
• Molekulargewicht: 312.400 g/mol
• XLogP3: 3.700
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 312.093 Da
• Monoisotopic Mass: 312.093 Da
• Topological Polar Surface Area: 83.400 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 433.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1