Necrox-2 - ≥98% , CAS No.1120333-38-1

CAS: 1120333-38-1 Cat. No.: N386066 Molecular Weight: 516.67

GRADE & PURITY ≥98%

Synonyms

Necrosis Inhibitor | [5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(1-methanesulfonyl-piperidin-4-yl)-amine

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Necrox-2 is a cell-permeable necrosis inhibitor. Primarily localizes in mitochondria and also possesses antioxidant properties. Necrox-2 selectively blocks oxidative stress-induced necrotic cell death.
Necrox-2is a cell-permeable necrosis inhibitor and antioxidant

Specifications

Synonyms

Necrosis Inhibitor | [5-(1, 1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(1-methanesulfonyl-piperidin-4-yl)-amine

Specifications & Purity

≥98%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Molecular Weight: 516.67

Chemical and Physical Properties

• Solubility: Soluble in DMSO (＞ 10 mg/ml).

References

1. Jing Lin, Xueli Yang, Cizhong Jiang, Xiaoguang Liu, Jiejun Shi.  (2026)  Enhancing cancer susceptibility to disulfidptosis by inducing cell cycle arrest and impairing DNA repair.  Theranostics,  16  (2): (637).  [PMID:41346703] [10.7150/thno.122956]