NF449 octasodium - Moligand™, 10 mM in DMSO , CAS No.627034-85-9

CAS: 627034-85-9 Cat. No.: N1494635 Molecular Weight: 1505.06 PubChem CID: 6093161

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

NF449 octasodium is a highly potent P2X 1 receptor antagonist, with IC 50 s of 0.28, 0.69, and 120 nM for rP2X 1 , rP2X 1+5 , P2X 2+3 , respectively. NF449 octasodium is a G sα -selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP binding to G sα-s , inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to G s .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Argon charged, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

ANTAGONIST

Names and Identifiers

• Isomeric SMILES: C1=CC(=C(C=C1S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C2=CC(=CC(=C2)NC(=O)NC3=CC(=CC(=C3)C(=O)NC4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC5=C(C=C(C=C5)S(=O)(=O)[O-])S(=O)(=O)[O-])C(=O)NC6=C(C=C(C=C6)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
• PubChem CID: 6093161
• Molecular Weight: 1505.06