NHS-PEG-NHS - MW 6000 Da

Cat. No.: N164064

GRADE & PURITY MW 6000 Da

Synonyms

Bis-succinimidyl PEG Ester

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Übersicht

N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol (PEG-NHS) is an amino (-NH₂) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with their available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our succinimidyl carbonate (SC) functionalized mPEG-NHS offers superior reactivity and higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.

Specifications

Synonyme

Bis-succinimidyl PEG Ester

Spezifikationen & Reinheit

MW 6000 Da

Biochemische und physiologische Mechanismen

Generally, a 10 to 50-fold molar excess of NHS PEG over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

• Conjugation buffer: Sodium bicarbonate 100 mM buffer, pH 8.5 or other amine-f

Storage

Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in regular aqeous solution as well as most organic solvents
• Empfindlichkeit: Moisture sensitive