Nicotinic acid mononucleotide - ≥95% , CAS No.321-02-8

CAS: 321-02-8 Cat. No.: N487022 Summenformel: C₁₁H₁₄NO₉P Molekulargewicht: 335.2

GRADE & PURITY ≥95%

Synonyms

3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium | nicotinic acid mononucleotide | NaMN | [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate | nicotinate mononucleotide | A-Nicotinic Acid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Nicotinic acid mononucleotide (NaMN) is formed from nicotinic acid 5-phosphoribosyl-1-pyrophosphate (PRPP) in the Preiss-Handler pathway in the presence of enzyme phosphoribosyltransferase (NaPRT).Nicotinic acid mononucleotide has been used as a substrate for NMN/NaMN adenylyltransferase (NMNAT) during nicotinamide adenine dinucleotide (NAD) biosynthesis.

Specifications

Synonyme

3-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium | nicotinic acid mononucleotide | NaMN | [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate | nicotinate mononucleotide | A-Nicotinic Acid

Spezifikationen & Reinheit

≥95%

Biochemische und physiologische Mechanismen

Nicotinic acid mononucleotide (NaMN) may be used to study the relationship between the phosphate-responsive signaling (PHO) pathway and nicotine adenine dinucleotide (NAD(+)) metabolism in yeast. Nicotinate mononucleotide is a substrate for NMN/NaMN adeny

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥95%

Namen und Kennungen

Pubchem Sid

504763523

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504763523

Kanonisches Lächeln

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)O

IUPAC Name

[(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChIKey

JOUIQRNQJGXQDC-ZYUZMQFOSA-N

INCHI

1S/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/m1/s1

Isomere SMILES

C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)O

Molekulargewicht

335.2

Reaxy-Rn

57922182

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=57922182&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Klasse Pyridine nucleotides
      • Subclass Nicotinic acid nucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Klasse: Pyridine nucleotides
• Subclass: Nicotinic acid nucleotides
• Intermediate Tree Nodes: Not available
• Direct Parent: Nicotinic acid nucleotides
• Alternative Parents: Pentose phosphates Glycosylamines Monosaccharide phosphates Pyridinecarboxylic acids Alkaloids and derivatives Monoalkyl phosphates Pyridinium derivatives Vinylogous amides Tetrahydrofurans Heteroaromatic compounds Secondary alcohols 1,2-diols Carboxylic acid salts Oxacyclic compounds Azacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Organic zwitterions Organopnictogen compounds Organic salts Hydrocarbon derivatives Organic oxides Organonitrogen compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Nicotinic-acid-nucleotide - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - Monosaccharide phosphate - Pentose monosaccharide - Pyridine carboxylic acid - Alkaloid or derivatives - Pyridine carboxylic acid or derivatives - Monoalkyl phosphate - Monosaccharide - Organic phosphoric acid derivative - Phosphoric acid ester - Pyridine - Pyridinium - Alkyl phosphate - Vinylogous amide - Tetrahydrofuran - Heteroaromatic compound - Carboxylic acid salt - Secondary alcohol - 1,2-diol - Azacycle - Oxacycle - Carboxylic acid - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Organic salt - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Alcohol - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic zwitterion - Aromatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as nicotinic acid nucleotides. These are pyridine nucleotides, in which the pyridine base is nicotinic acid or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y