NMDA (N-Methyl-D-aspartic acid)(NMDA) - Moligand™, 10mM in DMSO , Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agonist of GluN2D, CAS No.6384-92-5, Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agonist of GluN2D

CAS: 6384-92-5 Cat. No.: N407747 Summenformel: C₅H₉NO₄ Molekulargewicht: 147.13 Beilstein Registry Number: 1724431

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

D-Aspartic acid, N-methyl-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

NMDA（N-Methyl-D-aspartic acid）is a specific agonist forNMDAreceptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Phase 4.
In vitro

NMDA is an excitatory amino acid neurotransmitter, which only binds to the NMDA receptor without effecting other glutamate receptors (such as those for AMPA and kainate). NMDA specifically binds to the NR2 subunits of NMDA receptor, and then stimulates the open of non-specific cation channel which can allow the passage of Ca²⁺ and Na⁺ into the cell and K⁺ out of the cell. Activation of the NMDA receptor is able to produce the excitatory postsynaptic potential (EPSP), and trigger the increase of intracellular Ca²⁺ content which may further take participating in various signaling pathways. NMDA receptor plays a key role in a wide range of physiological (e.g. long-term potentiation and neuronal plasticity) and pathological processes (e.g. excitotoxicity and epilepsy).

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥100%

Specifications

Synonyme

D-Aspartic acid, N-methyl-

Spezifikationen & Reinheit

Moligand™, 10mM in DMSO

Biochemische und physiologische Mechanismen

NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Phase 4.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

AGONIST

Mechanismus der Wirkung

Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agonist of GluN2D

Namen und Kennungen

Isomere SMILES

CN[C@H](CC(=O)O)C(=O)O

RTECS

CI9457000

Molekulargewicht

147.13

Beilstein

1724431

Reaxy-Rn

1724430

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1724430&ln=

Zugehörige Ziele (menschlich)

HPN Tchem Serine protease hepsin (0 Activities)

Discover Target: HPN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 58 mg/mL (199.81 mM); Ethanol: 15 mg/mL warmed with 50ºC Water: bath (51.67 mM); Water: Insoluble
• Spezifische Drehung [α]: -15° (C=2,H2O)
• Schmelzpunkt (°C): 178 °C

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 6384-92-5, the molecular formula is C5H9NO4, and the molecular weight is 147.13 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.