Papain, CAS No.9001-73-4

CAS: 9001-73-4 Cat. No.: P164463 EC Number: 232-627-2

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Carica papaya; ≥2000U/mg enzyme powder，with casein as substrate

Accession #

P00784

Bioactivity

≥2000U/mg enzyme powder

Overview

Papain is a 100% natural bioenzyme product extracted from the unripe fruits of Carica papaya L. via advanced bioengineering technologies. Composed of 212 amino acid residues with a molecular weight of 21,000 Da, it is classified as a thiol (-SH)-containing endopeptidase. Endowed with both proteolytic and esterolytic activities, papain exhibits broad substrate specificity—exerting potent hydrolytic effects on animal/plant proteins, polypeptides, esters, and amides. Notably, it also possesses synthetic capability, enabling the resynthesis of proteinaceous substances from protein hydrolysates. This unique property can be harnessed to enhance the nutritional value or functional characteristics of animal and plant proteins.

Product Features

1. Advanced Processing Technologies: Integration of state-of-the-art bioengineering, membrane separation, and vacuum freeze-drying technologies, coupled with proprietary enzyme stabilization technology, minimizes enzyme activity loss during manufacturing.

2. Stringent Quality Compliance: Manufactured in accordance with United States Pharmacopeia (USP) standards and current Chinese national standards. A rigorous quality control system, aligned with international quality certification requirements, ensures strict microbial limits, meeting the national hygiene standards for export food.

3. High-Efficiency Ultrafiltration Separation: Optimized ultrafiltration technology for papain purification enables the extraction of high-purity papain under ambient temperature conditions, achieving a protease recovery rate of over 90%. This significantly improves yield and reduces production costs.

Product Appearance: Pale yellow or white solid powder

Application Fields

1. Food Industry

Leveraging its enzymatic catalysis, papain hydrolyzes macromolecular proteins in food into small-molecule peptides and amino acids for easy absorption. It is widely used in:

Hydrolysis of animal/plant proteins (chicken, pork, beef, seafood, blood products, soybean, peanut, etc.)

Meat tenderizer, wine clarifier, biscuit crisping agent, noodle stabilizer

Health food production, soy sauce brewing, and wine fermentation starter

Papain not only enhances the nutritional value of food but also reduces production costs.

2. Biscuit Industry

Reduces dough gluten viscosity, improves dough plasticity and physicochemical properties.

Hydrolyzes macromolecular proteins into short peptides and amino acids, facilitating the Maillard reaction between sugars and amino compounds—resulting in faster color development, a bright, glossy, and appetizing appearance, enhanced crispness, and a distinct reticular cross-section with clear layers.

Lowers biscuit cracking and breakage rates, yielding well-shaped, plump, non-shrinking biscuits with sharp patterns and smooth surfaces.

Reduces the usage of sodium metabisulfite by 10%–25%, thereby decreasing residual harmful substances such as SO₂. It also mitigates the negative impact of chemical additives on biscuit flavor, significantly improving product quality.

3. Pharmaceutical Industry

Drugs formulated with papain (e.g., papain throat lozenges, enteric-coated tablets/capsules, buccal tablets) exhibit anti-inflammatory, cholagogic, analgesic, digestive-aiding, and immunity-boosting effects. Further research indicates its potential applications in:

Red blood cell surface analysis and blood group identification

Treatment of gynecological disorders, glaucoma, and insect bites

4. Textile Industry

Wool Shrink-Resistant Finishing: Wool treated with papain demonstrates higher tensile strength than conventionally processed wool, with a soft, comfortable handfeel and zero shrinkage.

Silk Degumming and Refining: Effective for degumming raw silk and refining silk fibers.

5. Leather Industry

Papain-based depilatory agents are used in leather tanning processes, producing leather with fine, smooth, and glossy pores.

6. Feed Industry

Hydrolyzes feed proteins into amino acids, increasing nutrient solubility and improving absorption and utilization in poultry.

Supplements endogenous enzyme deficiencies in animals, enhancing feed conversion efficiency and reducing feed costs.

Stimulates appetite, promotes animal growth, and increases daily weight gain and survival rates.

Can be used as an additive in high-grade compound fertilizers for fruits and vegetables.

7. Daily Chemical Industry

Incorporated into soaps, detergents, laundry powders, and hand sanitizers, papain effectively removes stubborn stains such as blood, milk, fruit juice, soy sauce, and grease—stains that are typically difficult to eliminate with ordinary detergents. It enhances detergency, provides bactericidal and disinfectant effects, and ensures safe use.

8. Cosmetic Industry

Skin Rejuvenation: Acts on aged cuticle cells, promoting their decomposition and exfoliation to achieve a skin-smoothing effect and stimulate cell proliferation. Papain hydrolysates form a film of amino acid derivatives on the skin surface, maintaining skin hydration and smoothness.

Whitening and Spot Lightening: Easily chelates copper ions in melanin (the key pigment causing skin spots), reducing melanin synthesis and fading existing spots. Additionally, tripeptides derived from papain hydrolysis directly inhibit the activity of tyrosinase (the enzyme responsible for melanin production) and scavenge free radicals, thereby achieving whitening and spot-removing effects.

9. Other Applications

Added to toothpaste, mouthwash, and tooth powder for oral hygiene, effectively removing dental plaque and tartar.

Formulated with other solvents to produce cleaning and disinfecting agents for contact lenses.

Used in the recovery of silver from photographic films.

Recommended Application Conditions

Optimum Temperature: 50–55℃

Optimum pH: 6.5

Optimum Dosage: Must be adjusted according to specific production conditions.

Storage Instructions

Store in a cool, dry, and dark place. Prolonged storage or adverse storage conditions (e.g., high temperature and humidity) may cause varying degrees of enzyme activity loss. In such cases, the dosage should be appropriately increased during application.

Safety Precautions

As a natural enzyme preparation and protein, papain is safe for human consumption—equivalent to consuming protein-rich foods—and offers nutritional benefits.

High-concentration papain powder or mists may trigger allergic reactions in sensitive individuals. Prolonged contact may cause irritation to the skin, eyes, and mucous membranes. Wear protective equipment such as masks and goggles during operation. Promptly clean up any excess or spilled enzyme powder: sweep large spills gently back into containers; use a vacuum cleaner or damp cloth to clean small spills.

Papain is a biologically active substance susceptible to inhibition or inactivation by heavy metal ions (Fe³⁺, Cu²⁺, Hg⁺, Pb⁺, etc.) and oxidizing agents. Avoid contact with these substances during storage and application.

Specifications

Product Name

Papain, CAS No.9001-73-4

Synonyms

2-(3-azaniumylpropanoylamino)-3-(1H-imidazol-5-yl)propanoate | Papaya peptidase I | Papainase | PPI | Papain

Grade

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Specifications & Purity

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Carica papaya; ≥2000U/mg enzyme powder，with casein as substrate

Biochemical and Physiological Mechanisms

Cysteine proteinase with a high level of diversity in substrate specificity, an amino acid bearing a large hydrophobic side chain at the P2 position is preferred. Catalytic activity: Hydrolysis of proteins with broad specificity for peptide bonds, but pre

Bioactivity

≥2000U/mg enzyme powder

Accession #

P00784

Predicted molecular weight

21 kDa

CAS

9001-73-4

Enzyme Commission Number

3.4.22.2

Molecule Type

Enzyme

Storage and Shipping

Concentration

from Carica papaya; ≥2000U/mg enzyme powder，with casein as substrate

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Unit definition

Ultraviolet Spectrophotometry: One enzyme activity unit (expressed as u/g) is defined as the quantity of enzyme required to hydrolyze casein under the specified assay conditions (37±0.2 °C, pH 7.0) and release trichloroacetic acid-soluble substances, whos

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56. Fu Rao, Dong Congcong, Sun Changmei, Qu Rongjun, Ji Chunnuan, Zhang Ying.  (2018)  Preparation of Porous m-aramid/cellulose Blend Membranes with High Moisture and Air Permeability by an Enzymatic Degradation Method.  FIBERS AND POLYMERS,  19  (6): (1150-1156).  [PMID:] [10.1007/s12221-018-1097-1]

57. Yanan Yuan, Chunliu Yang, Tianwei Lv, Fengxia Qiao, Yang Zhou, Hongyuan Yan.  (2018)  Green synthesis of hydrophilic protein-imprinted resin with specific recognition of bovine serum albumin in aqueous matrix.  ANALYTICA CHIMICA ACTA,      [PMID:30172329] [10.1016/j.aca.2018.06.009]

58. Shanshan Wang, Yingyi Wang, Xiaoming Yang.  (2018)  Identifying three routes of the sensing mechanism for casein-directed gold nanoclusters.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:29803150] [10.1016/j.colsurfb.2018.05.034]

59. Yuanzi Wu, Zhen Cai, Shuigen Wu, Wenli Xiong, Shanyun Ma.  (2018)  Protein purification by chemo-selective precipitation using thermoresponsive polymers.  BIOPOLYMERS,  109  (6): (e23222).  [PMID:29732533] [10.1002/bip.23222]

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61. Yan-Jie Gu, Min-Liang Zhu, Yan-Li Li, Chun-Hua Xiong.  (2018)  Research of a new metal chelating carrier preparation and papain immobilization.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:29454943] [10.1016/j.ijbiomac.2018.02.079]

62. Ling Wang, Hao Shen, Jichang Nie, Dichen Li, Hongbin Fan, Zhongmin Jin, Chaozong Liu.  (2017)  Functional testing on engineered cartilage to identify the role played by shearing.  MEDICAL ENGINEERING & PHYSICS,      [PMID:29239747] [10.1016/j.medengphy.2017.10.011]

63. Wei Chen, Rui Wang, Tingting Xu, Xuebin Ma, Zhong Yao, Bo Chi, Hong Xu.  (2017)  A mussel-inspired poly(γ-glutamic acid) tissue adhesive with high wet strength for wound closure.  Journal of Materials Chemistry B,  5  (28): (5668-5678).  [PMID:] [10.1039/C7TB00813A]

64. Yufang Hu, Qingqing Zhang, Zhiyong Guo, Sui Wang, Chunnuan Du, Chunyang Zhai.  (2017)  In situ grown DNA nanotail-templated silver nanoclusters enabling label-free electrochemical sensing of terminal deoxynucleotidyl transferase activity.  BIOSENSORS & BIOELECTRONICS,      [PMID:28662471] [10.1016/j.bios.2017.06.017]

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68. Mufang Li, Mengying Luo, Fei Li, Wenwen Wang, Ke Liu, Qiongzhen Liu, Yuedan Wang, Zhentan Lu, Dong Wang.  (2016)  Biomimetic Copper-Based Inorganic–Protein Nanoflower Assembly Constructed on the Nanoscale Fibrous Membrane with Enhanced Stability and Durability.  Journal of Physical Chemistry C,      [PMID:] [10.1021/acs.jpcc.6b03537]

69. Bin Yang, Sifang Lv, Feng Chen, Chan Liu, Changqun Cai, Chunyan Chen, Xiaoming Chen.  (2016)  A resonance light scattering sensor based on bioinspired molecularly imprinted polymers for selective detection of papain at trace levels.  ANALYTICA CHIMICA ACTA,      [PMID:26920781] [10.1016/j.aca.2016.01.030]

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71. Jiao-Jiao Yuan, Cheng-Zhang Wang, Jian-Zhong Ye, Ran Tao, Yu-Si Zhang.  (2015)  Enzymatic Hydrolysis of Oleuropein from Olea europea (Olive) Leaf Extract and Antioxidant Activities.  MOLECULES,  20  (2): (2903-2921).  [PMID:25679050] [10.3390/molecules20022903]

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76. Zeguo Feng, Shan Lu, Ying He, Yanting Sun, Lei Ma, Hui Guo, Yiting Kang, Rui Xu, Yifei Song, Lei Huang, Liguo Qin, Jianbao Zhang, Yali Zhang.  (2025)  A dual-network hydrogel patch fabricated by alginate/sulfobetaine methacrylate enriched with Dictyophora indusiata β-glucans promotes diabetic wound repair.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40139598] [10.1016/j.ijbiomac.2025.142495]

77. Jingjing Shen, Long Zheng, Guangning Chen, Achiraya Khamleng, Changhu Xue, Yaoguang Chang.  (2025)  A novel endo-1,3-fucanase in glycoside hydrolase family 187 provided a biotechnological tool for preparing sulfated fucan oligosaccharides.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39965693] [10.1016/j.ijbiomac.2025.141171]

78. Du Mengdi, Yu Wei, Ding Ning, Jian Mengqi, Cheng Yongqiang, Gan Jing.  (2024)  Antioxidant, aroma, and sensory characteristics of Maillard reaction products from Urechis unicinctus hydrolysates: development of food flavorings.  Frontiers in Nutrition,      [PMID:38379540] [10.3389/fnut.2024.1325886]

79. Runfeng Cao, Zhenying Chen, Qing Ye, Weiyan Sun, Weikang Lin, Hai Tang, Xingseng Yang, Junhao Liang, Yi Chen, Lei Wang, Qingfeng Bai, Ziying Pan, Yulong Hu, Dong Xie, Deping Zhao, Yong Hu, Chang Chen.  (2024)  Aptamer-Directed Bidirectional Modulation of Vascular Niches for Promoted Regeneration of Segmental Trachea Defect.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202409071]

80. Bing Zheng, Tianxiang Ao, Xiaole Zhao, Yi Chen, Jianhua Xie, Xingcai Gao, Li Liu, Xiaobo Hu, Qiang Yu.  (2024)  Comprehensive assessment of the anti-obesity effects of highland barley total, insoluble, and soluble dietary fiber through multi-omics analysis.  FOOD RESEARCH INTERNATIONAL,      [PMID:38876588] [10.1016/j.foodres.2024.114535]

81. Xin Wen, Xin Zhang, Wanting Wang, Fuqiang Zhao, Mingyong Xie, Guomin Pei, Jun Cao, Hesham El-Seedi, Hui Ye, Jun Yang, Yuanping Zheng, Chuan Li.  (2025)  Effects of Holothuria leucospilota polysaccharide on alleviating diabetic kidney disease through regulating inflammation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40081694] [10.1016/j.ijbiomac.2025.142027]

82. Yu Bai, Zhuo Zhang, Jiawei Qiao, Xiaolong Liu, Shengyuan Guo, Genping Wang, Ting Zhang, Guohua Zhang, Guixing Ren, Lizhen Zhang.  (2024)  Establishment of near-infrared rapid prediction model and comprehensive evaluation model for foxtail millet quality.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2024.106769]

83. Lixiang Fang, Junchen Li, Xiaoxiao Chen, Xiangqun Xu.  (2024)  How lignocellulose degradation can promote the quality and function of dietary fiber from bamboo shoot residue by Inonotus obliquus fermentation.  FOOD CHEMISTRY,      [PMID:38696939] [10.1016/j.foodchem.2024.139479]

84. Shengyuan Guo, Chaofan Zhao, Jiankang Zhou, Zhuo Zhang, Wenting Wang, Yuting Zhu, Chuan Dong, Guixing Ren.  (2025)  Influence of the Nutritional Composition of Quinoa (Chenopodium quinoa Willd.) on the Sensory Quality of Cooked Quinoa.  Foods,  14  (6): (988).  [PMID:40232004] [10.3390/foods14060988]

85. Yulong Wu, Jin Zhang, Ruikai Zhu, Hong Zhang, Dapeng Li, Huanhuan Li, Honggang Tang, Lihong Chen, Xinyan Peng, Xianrong Xu, Ke Zhao.  (2024)  Mechanistic Study of Novel Dipeptidyl Peptidase IV Inhibitory Peptides from Goat’s Milk Based on Peptidomics and In Silico Analysis.  Foods,  13  (8): (1194).  [PMID:38672866] [10.3390/foods13081194]

86. Yanyan Wang, Ruyu Yan, Hai Yang, Ying Liu, Xiupeng Zhong, Sa Liu, Renjian Xie, Li Ren.  (2024)  Modular microgel-based bioassembly scaffold induced chondrogenic and osteogenic differentiation of BMSCs.  MACROMOLECULAR BIOSCIENCE,      [PMID:38663437] [10.1002/mabi.202400051]

87. Xin Chen, Wenhao Liu, Chi Su, Jianyang Shan, Xiang Li, Yimin Chai, Yaling Yu, Gen Wen.  (2024)  Multimodal effects of an extracellular matrix on cellular morphology, dynamics and functionality.  Journal of Materials Chemistry B,      [PMID:39041314] [10.1039/D4TB00360H]

88. Jiaming Cao, Boyuan Xiang, Baojie Dou, Jingfei Hu, Lei Zhang, Xinxin Kang, Mingsheng Lyu, Shujun Wang.  (2024)  Novel Angiotensin-Converting Enzyme-Inhibitory Peptides Obtained from Trichiurus lepturus: Preparation, Identification and Potential Antihypertensive Mechanism.  Biomolecules,  14  (5): (581).  [PMID:38785988] [10.3390/biom14050581]

89. Jiajun Pan, Zhaopeng Xia, Haibao Zhang, Yang Lu, Yong Liu.  (2024)  One-step bleaching method for animal fiber by persulphate/hydrogen peroxide: Degradation mechanism of eumelanin.  Journal of Cleaner Production,      [PMID:] [10.1016/j.jclepro.2024.142256]

90. Zhendong Zhang, Jing Xiao, Chunyou Wang, Fangmiao Song, Wei Sun, Chenhui Wang, Zhisong Lu, Yan Zhang.  (2024)  Polydopamine-mediated in situ synthesis of gold nanoparticles uniformly distributed on silk fibers as reusable catalysts for efficient 4-nitrophenol reduction.  Journal of Industrial Textiles,      [PMID:] [10.1177/15280837241227626]

91. Yan Wang, Xiao Kong, Mengdi Du, Yang Qiao, Minjie Ye, Bing Han, Jing Gan.  (2024)  Preparation, Identification, and Digestive Stability of Antioxidant Peptides From Chlorella vulgaris.  JOURNAL OF FOOD BIOCHEMISTRY,  2024  (1): (3828251).  [PMID:] [10.1155/2024/3828251]

92. Huimei Wang, Chang Li, Yingzhi Li, Jiaming Gao, Xueping Leng, Danfei Huang.  (2025)  Preparation, physicochemical characterization and functional properties of selenium nanoparticles stabilized by polysaccharides from the seeds of Plantago asiatica L.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,      [PMID:39956988] [10.1002/jsfa.14127]

93. Fengfang Zhou, Binxin Cai, Shaojiang Ruan, Qi Wei.  (2024)  Purification, characterization, and antioxidant ability of polysaccharides from Phascolosoma esculentas.  Food Science & Nutrition,      [PMID:38628168] [10.1002/fsn3.3961]

94. Moran Huang, Yangfan Ding, Jize Dong, Guoqi Li, Guojian Fu, Jinhui Pang, Yaying Sun, Shanxing Zhang, Jinglei Wu, Jiwu Chen.  (2025)  Regional-Specific Decellularized Meniscus Extracellular Matrix Elastic Nanofiber Aerogels Regulate Meniscal Regeneration and Vascularization.  Advanced Healthcare Materials,      [PMID:39981969] [10.1002/adhm.202404626]

95. Bingqian Nie, Jianle Chen, Wenkang Wang, Tong Cao, Xingqian Ye, Shiguo Chen, Zhiqiang Hou.  (2025)  Structural and functional benefits of Ganoderma lucidum polysaccharides due to space mutagenesis.  CARBOHYDRATE POLYMERS,      [PMID:40383591] [10.1016/j.carbpol.2025.123532]

96. Fan-Yu He, Xing-Tong Zhu, Hui Liu, Yun-Q ing Chong, Zhi-Ping Wu, Lu-Jun Ye, Yue-Wen Chen, Jing-Jing Fu.  (2024)  Structural and sensory characteristics of ultrasonic assisted wet-heating Maillard reaction products of Giant salamander protein hydrolysates.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,      [PMID:39056251] [10.1002/jsfa.13769]

97. Jianhui Feng, Wenhao Cao, Bo Xu, Zhenhua Wang.  (2025)  Structure-based method for the discovery of selective inhibitors of PED 5 in erectile dysfunction therapy from the Pacific oyster peptides (Crassostrea gigas): Peptidomic analysis, molecular docking, and activity validation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39778840] [10.1016/j.ijbiomac.2025.139494]

98. Bing-Jie Chen, Yong-Jin Qiao, Gang Yu, Xiao Wang, Yi Zhang, Ling-Lin Fu.  (2024)  Sulfation, characterization, antibacterial activity, and action mechanism of rice bran polysaccharides.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.103953]

99. Tiantian Fu, Yu Zhang, Hongwei Cao, Xiao Guan.  (2024)  The effects of milling on the chemical forms, bioavailability, and in vivo distribution of Vitamin B1 in rice.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.105376]

100. Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan.  (2025)  The effects of milling-induced lipid oxidation on bioactive components in rice during storage.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.106057]

101. Bing Zheng, Xiaole Zhao, Tianxiang Ao, Yi Chen, Jianhua Xie, Xingcai Gao, Li Liu, Xiaobo Hu, Qiang Yu.  (2024)  The role of bound polyphenols in the anti-obesity effects of defatted rice bran insoluble dietary fiber: An insight from multi-omics.  FOOD CHEMISTRY,      [PMID:38986204] [10.1016/j.foodchem.2024.140345]

102. Zhenhao Zhao, Junbo Hu, Huimin Cui, Tianrui Zhao, Yaping Liu, Zhengxuan Wang, Guiguang Cheng.  (2025)  Tyrosinase inhibition and enzyme kinetics red rice bran protein peptides: mechanism, identification, in silico exploration, and experimental validation.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.106319]

103. Ruixia Chen, Kakhramon Davranov, Nigora Rustamova, Weizheng Sun, Xiao-Chen Liu.  (2025)  Exploring the salt taste-enhancing activity of key peptides and ultrafiltrated fractions from spent hen meat hydrolysate.  FOOD CHEMISTRY,      [PMID:40639252] [10.1016/j.foodchem.2025.145444]

104. Shenji Yang, Xiaojun Huang, Xiajialong Li, Jing Feng, Peng Chen, Zhikang Cao, Luyao He, Chaojun Li, Zhipeng Li, Ming-Yong Xie.  (2025)  Aloe vera polysaccharides mitigate high-fat high-cholesterol diet-induced atherosclerosis in ApoE-/- mice via regulation of lipid metabolism and gut microbiota.  Food & Function,      [PMID:40726156] [10.1039/D5FO01995H]

105. Lansha Song, Keting Li, Lian Shuai, Sha Li, Xinyao Wei, Xingyi Chen, Lei Wang.  (2025)  Fabrication and characterization of citrus pectin/Dictyophora Rubrovalvata polysaccharide films: pH-cycle treatment and Penaeus vannamei shelf-life extension.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2025.111879]

106. Zhongyu Yang, Jingyang Guo, Keying Song, Gaoshang Wang, Jian Guo, Zhili Wan, Xiaoquan Yang.  (2025)  Plant cheese based on complex coacervation with enrichment of oleosomes.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2025.111994]

107. Qin Yang, Zhenkun Zhang, Lin Wang, Xiwen Xing, Jiahai Zhou, Long Li.  (2023)  Preparation and Characterization of Metal–Organic Framework Coatings for Improving Protein Crystallization Screening.  Nanomaterials,  13  (14): (2064).  [PMID:37513075] [10.3390/nano13142064]

108. Yang Xiaoliang, Huo Chaofei, Ji Yuting, Xu Sheng, Zhang Cuige, Xia Chunmiao, Liu Huan, Zhang Rongli, Jin Ying, Miao Zongcheng.  (2023)  A molecularly imprinted sensor based on thermo-responsive calcium alginate nanohydrogels for lysozyme detection.  COLLOID AND POLYMER SCIENCE,  301  (3): (229-237).  [PMID:] [10.1007/s00396-023-05062-9]

109. Jun Huang, Gang Yang, Kewei Chen, Muying Du, Zsolt Zalán, Ferenc Hegyi, Jianquan Kan.  (2024)  Anti-fungal effects of lactic acid bacteria from pickles on the growth and sterigmatocystin production of Aspergillus versicolor.  INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY,      [PMID:38955023] [10.1016/j.ijfoodmicro.2024.110809]

110. Jianjie Wu, Yuanyuan Zhang, Ping Sheng, Chunjiao He, Hao Liu, Shanyong Gu, Jiaoyang Luo, Meihua Yang.  (2025)  Ion-pairing reversed-phase chromatography with inductively coupled plasma-mass spectrometry applied to simultaneous determination of arsenic and selenium species in functional food American ginseng.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,      [PMID:40040335] [10.1002/jsfa.14211]

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112. Haibin Yuan, Tianyang Wang, Lan Xiao, Hongfeng Jia, Huachang Wu, Ping Dong.  (2025)  Comprehensive Analysis of Volatile and Nonvolatile Compounds in Dictyophora indusiata Hydrolysates.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.117737]

113. Le-Yu Huang, Huiling Wang, Yue-Yang Zhang, Shi-Yu Liu.  (2025)  An acylaminoacyl-peptide hydrolase-activated fluorescent probe for ultrasensitive detection of pesticide residue.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:40188572] [10.1016/j.saa.2025.126152]

114. Gongda Wang, Xiangbo Ren, Junyi Liu, Wenjuan Wang, Cui Zhang, Chunlong Yuan, Junjun Li.  (2025)  Functional properties of insoluble dietary fibers extracted from different grape pomaces during simulated digestion and in vitro fermentation.  Food & Function,      [PMID:40271898] [10.1039/D4FO06074A]

115. Ruikai Zhu, Hong Zhang, Yulong Wu, Huanhuan Li, Honggang Tang, Xianrong Xu, Ke Zhao.  (2025)  Exploration and molecular mechanism of novel ACE inhibitory peptides from goat milk protein: A combined in silico and in vitro study.  INTERNATIONAL DAIRY JOURNAL,      [PMID:] [10.1016/j.idairyj.2025.106265]

116. Yuanyuan Li, Xiaoxue Chen, Gongda Wang, Linting Xu, Yichen Liu, Chunlong Yuan, Junjun Li.  (2025)  The release patterns and potential prebiotic characteristics of soluble and insoluble dietary fiber-bound polyphenols from pinot noir grape pomace in vitro digestion and fermentation.  Food Chemistry-X,      [PMID:40642527] [10.1016/j.fochx.2025.102694]

117. Huihui Ju, Yile Zhou, Wanting Wei, Yan Hu, Hongwei Fang, Zhouyi Chen, Xia Sun, Yi Shi, Hao Fang.  (2025)  Ageing-associated gut dysbiosis deteriorates mouse cognition: Ageing-associated gut dysbiosis deteriorates mouse cognition.  ACTA BIOCHIMICA ET BIOPHYSICA SINICA,  57  (8): (1234).  [PMID:39943805] [10.3724/abbs.2024217]

118. Wanting Wang, Kexue Zhu, Jun Cao, Shunjiang Zeng, Lijun You, Chao Zhao, Yuanping Zheng, Chuan Li.  (2025)  Structural Characterization and Physicochemical Property of a Purified Fucosylated Glycosaminoglycan Sulfate From Holothuria leucospilota.  eFood,  6  (4): (e70071).  [PMID:] [10.1002/efd2.70071]

119. Dong-Wei Shao, Tong Xie, Ya-Tao Wang.  (2025)  A pH-responsive injectable hydrogel that modulates the inflammatory microenvironment for the treatment of osteoarthritis.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41176002] [10.1016/j.ijbiomac.2025.148686]

120. Jun-Hui Du, Yu-Yun Xiao, Ying-Chao Guo, Wen-Qing Zhang, Guan-Ru Si, Zheng-Fang Wu, Chuan-Qiang Gao, Jie Mei, Yi-Long Ma, Zhao-Jun Wei.  (2025)  Identification and Inhibitory Mechanisms of Anti-α-glucosidase Peptides from Xiaojiao Baijiu Distillers’ Grains.  ACS Food Science & Technology,      [PMID:] [10.1021/acsfoodscitech.5c00605]

121. Haotian Chen, Zimo Chen, Hanbing Yao, Yujuan Zhan, Binyu Xiao, Shuangshuang Liu, Jiayi Yan, Yifu Li, Chang Shu.  (2025)  A self-calibrating fluorescence / colorimetric dual-mode sensor based on MIL-101(Fe) for specifical dopamine detection in human serum.  TALANTA,      [PMID:41308607] [10.1016/j.talanta.2025.129151]

122. Han Lichun, Zhong Xiufang, Fu Zhilei, Yan Jinlong, Xiao Lin, Liu Xiaoyan, Rana Abdul Basit, Wang Jinpeng, Yin Dafeng, Fan Guangsen.  (2025)  Application of feruloyl esterase BpFae03105 and xylanase XynAS Co-enzymolysis to produce ferulic acid from wheat bran.  Biocatalysis and Agricultural Biotechnology,      [PMID:] [10.1016/j.bcab.2025.103868]

123. Long Sun, Yiqing Jia, Min Jiang, Renfeng Ye, Zhengxuan Wang, Guiguang Cheng, Yaping Liu.  (2025)  Tailoring purple rice bran protein via multi-modal modifications: Chemical, physical, and enzymatic strategies for enhanced functionality.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41271049] [10.1016/j.ijbiomac.2025.149047]

124. Yuling Chen, Xueluan Liu, Genglin Lu, Xuan He, Dandan Li, Yunong Tian, Xiaolin Feng, Yong Ye.  (2025)  Properties of Novel Components of Polysaccharides Isolated From Lycium barbarum Fruits.  International Journal of Food Science,  2025  (1): (4899439).  [PMID:41324086] [10.1155/ijfo/4899439]

125. Zhouya Bai, Yunhui Zhang, Honglin Lan, Xingguo Li, Jiahao Wan, Yanbin Wang, Jinying Guo, Denglin Luo.  (2025)  Effects of Chinese yam and its peel polysaccharides on blood glucose and lipids in type 2 diabetic mice.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41344459] [10.1016/j.ijbiomac.2025.149445]

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