Paxilline - Moligand™, 10 mM in DMSO , CAS No.57186-25-1

CAS: 57186-25-1 Cat. No.: P1499990 Molecular Weight: 435.56 EC Number: 637-206-0 PubChem CID: 105008

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Paxilline is an indole alkaloid mycotoxin derived from Penicillium paxilli, which effectively inhibits the BK channel through a channel-blocking mechanism. Paxilline also inhibits sarco/endoplasmic reticulum Ca 2+ -stimulated ATPase (SERCA) , with IC 50 values ranging from 5 μM to 50 μM for different SERCA isoforms. Paxilline exhibits significant anticonvulsant and neuroprotective effects, as well as certain antioxidant activity .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Names and Identifiers

• Isomeric SMILES: C[C@]12CC[C@H]3C(=CC(=O)[C@H](O3)C(C)(C)O)[C@@]1(CC[C@@H]4[C@@]2(C5=C(C4)C6=CC=CC=C6N5)C)O
• WGK Germany: 3
• RTECS: DJ2830000
• PubChem CID: 105008
• Molecular Weight: 435.56

Chemical and Physical Properties

• Melt Point(°C): 252°C-269°C