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· · COA & SDS für jedes Produkt verfügbar · Versand am selben Tag auf Lager PD 146176 - Moligand™, ≥98%(HPLC) , Inhibitor of 15-LOX-1, CAS No.4079-26-9, Inhibitor of 15-LOX-1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) Synonyms
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
Specifications Synonyme
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Spezifikationen & Reinheit
Moligand™, ≥98%(HPLC)
Biochemische und physiologische Mechanismen
PD 146176 blocks neuroprotectin D1 (NPD1) and eicosanoid synthesis by inhibiting the 5-lipoxygenase-1 (15-LOX-1) enzyme.
15-Lipoxygenase inhibitor
Verschickt in
Ice chest + Ice pads
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Mechanismus der Wirkung
Inhibitor of 15-LOX-1
Namen und Kennungen Pubchem Sid 504758372 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504758372 Kanonisches Lächeln C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24 IUPAC Name 6,11-dihydrothiochromeno[4,3-b]indole InChIKey ZGOOPZVQMLHPFM-UHFFFAOYSA-N INCHI 1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2 Isomere SMILES C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24 Alternative CAS-Nummer 4079-26-9 PubChem CID 297589 NSC-Nummer 168807 MeSH-Eintrag 6,11-dihydro-5-thia-11-aza-benzo(a)-fluorene;PD 146176;PD-146176 Molekulargewicht 237.32
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Klasse Indoles and derivatives Subclass Indoles Intermediate Tree Nodes Not available Direct Parent 3-alkylindoles Alternative Parents 1-benzothiopyrans Alkylarylthioethers Benzenoids Pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 3-alkylindole - 1-benzothiopyran - Benzothiopyran - Aryl thioether - Alkylarylthioether - Benzenoid - Heteroaromatic compound - Pyrrole - Azacycle - Thioether - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound Beschreibung This compound belongs to the class of organic compounds known as 3-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 3-position. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Löslichkeit Solvent:DMSO, Max Conc. mg/mL: 23.73, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 11.87, Max Conc. mM: 50 Molekulargewicht 237.320 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 1 Rotatable Bond Count 0 Exact Mass 237.061 Da Monoisotopic Mass 237.061 Da Topological Polar Surface Area 41.100 Ų Heavy Atom Count 17 Formal Charge 0 Complexity 293.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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