≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Lagerung bei -20°C Ships Eistruhe + Eispads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht
PF-06409577 ist ein 6-Chlorindol-Derivat, das aus 5-Brom-6-Chlorindol gewonnen wird. PF-06409577 wurde verwendet, um sein Potenzial als therapeutisches Mittel bei diabetischer Nephropathie zu ermitteln.
PF-06409577 schützt die Zellen des retinalen Pigmentepithels vor UV-Strahlung, indem es die AMPK-Signalübertragung (AMP-aktivierte Proteinkinase) aktiviert. Es ist oral bioverfügbar und besitzt pharmakokinetische Eigenschaften. PF-06409577 blockiert die D
This compound belongs to the class of organic compounds known as indolecarboxylic acids and derivatives. These are compounds containing a carboxylic acid group (or a derivative thereof) linked to an indole.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Solvent:DMSO, Max Conc. mg/mL: 34.18, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 6.84, Max Conc. mM: 20
Molekulargewicht
341.800 g/mol
XLogP3
3.600
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
3
Exact Mass
341.082 Da
Monoisotopic Mass
341.082 Da
Topological Polar Surface Area
73.300 Ų
Heavy Atom Count
24
Formal Charge
0
Complexity
487.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Lösungsrechner
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What is the purity of this product, and how is it determined?
This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1467057-23-3, the molecular formula is C19H16ClNO3, and the molecular weight is 341.79 g/mol. InChIKey FHQXLWCFSUSXBF-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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