PLX7922 - 10mM in DMSO , CAS No.1638772-61-8

CAS: 1638772-61-8 Cat. No.: P656692 Summenformel: \n C₂₀H₂₅FN₆O₂S₂ Molekulargewicht: 464.58 PubChem CID: 91971376

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

PLX7922, a RAF inhibitor, can bind with BRAF V600E . PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK in mutant NRAS cell lines

In Vitro

PLX7922 (1-1000 nM) inhibits pERK in BRAF V600E cell lines, activates pERK in mutant NRAS cell lines (B9 and IPC-298). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:RAF

Specifications

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

PLX7922, a RAF inhibitor, can bind with BRAF V600E . PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK in mutant NRAS cell lines.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

• Isomere SMILES: CCN(C)S(=O)(=O)NC1=CC=CC(=C1F)C2=C(SC(=N2)C(C)(C)C)C3=NC(=NC=C3)N
• PubChem CID: 91971376
• Molekulargewicht: 464.58