Poly(N-isopropylacrylamide) - Mn 40,000 , CAS No.25189-55-3

CAS: 25189-55-3 Cat. No.: P303215 EC Number: 805-716-4

GRADE & PURITY Mn 40,000

Synonyms

PNIPAM | AS-18956 | Isopropyl acrylamide | 2-Propenamide, N-(1-methylethyl)- | N-ISOPROPYLACRYLAMIDE [HSDB] | n-isopropylpropenamide | NSC11448 | NSC-11448 | ISOPROPYLACRYLAMIDE [INCI] | N-Isopropylacrylamide, >=99% | D70366 | FT-0700646 | N-Isopropylacry

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Product Application：

PolyNIPAM is a stimuli-responsive polymer. The low PDI means that the distribution of chain lengths is narrow which will typically lead to better reproducibility. This polymer for development of thermosensitive coated micro/nano materials, including thermoresponsive polymeric drug delivery systems. Thermosensitive polymer, can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

Specifications

Synonyms

PNIPAM | AS-18956 | Isopropyl acrylamide | 2-Propenamide, N-(1-methylethyl)- | N-ISOPROPYLACRYLAMIDE [HSDB] | n-isopropylpropenamide | NSC11448 | NSC-11448 | ISOPROPYLACRYLAMIDE [INCI] | N-Isopropylacrylamide, >=99% | D70366 | FT-0700646 | N-Isopropylacry

Specifications & Purity

Mn 40, 000

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Pubchem Sid: 488182270
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488182270
• Canonical Smiles: CC(C)NC(=O)C=C
• IUPAC Name: N-propan-2-ylprop-2-enamide
• InChIKey: QNILTEGFHQSKFF-UHFFFAOYSA-N
• INCHI: 1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
• Isomeric SMILES: CC(C)NC(=O)C=C
• Reaxy-Rn: 1744926
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1744926&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Acrylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Acrylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Acrylic acids and derivatives
• Alternative Parents: Secondary carboxylic acid amides Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Acrylic acid or derivatives - Secondary carboxylic acid amide - Carboxamide group - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as acrylic acids and derivatives. These are organic compounds containing acrylic acid CH2=CHCO2H or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Molecular Weight: 113.160 g/mol
• XLogP3: 0.900
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 113.084 Da
• Monoisotopic Mass: 113.084 Da
• Topological Polar Surface Area: 29.100 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 96.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

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