Pomalidomide 4'-PEG4-acid - ≥95%(HPLC) , CAS No.2138440-81-8

CAS: 2138440-81-8 Cat. No.: P287891 Summenformel: C₂₄H₃₁N₃O₁₀ Molekulargewicht: 521.52 PubChem CID: 134589785

GRADE & PURITY ≥95%(HPLC)

Synonyms

Pomalidomide-PEG4-CO2H | 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid | Crosslinker–E3 Ligase ligand conjugate | Template for synthesis of targeted protein degrader | 3-[2-[2-[2-[2-[[2-(2,6-Dioxo-

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Specifications

Synonyme

Pomalidomide-PEG4-CO2H | 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid | Crosslinker–E3 Ligase ligand conjugate | Template for synthesis of targeted protein degrader | 3-[2-[2-[2-[2-[[2-(2,6-Dioxo-

Spezifikationen & Reinheit

≥95%(HPLC)

Biochemische und physiologische Mechanismen

An E3 ligase ligand and a PEG4 linker with terminal carboxylic acid were integrated to bind to the target protein ligand.

Storage

Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥95%(HPLC)

Namen und Kennungen

• Pubchem Sid: 488202805
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488202805
• Kanonisches Lächeln: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCC(=O)O
• IUPAC Name: 3-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChIKey: CAANPUBZFFRWQP-UHFFFAOYSA-N
• INCHI: 1S/C24H31N3O10/c28-19-5-4-18(22(31)26-19)27-23(32)16-2-1-3-17(21(16)24(27)33)25-7-9-35-11-13-37-15-14-36-12-10-34-8-6-20(29)30/h1-3,18,25H,4-15H2,(H,29,30)(H,26,28,31)
• Isomere SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCOCCOCCC(=O)O
• PubChem CID: 134589785
• Molekulargewicht: 521.52

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Molekulargewicht: 521.500 g/mol
• XLogP3: -0.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 17
• Exact Mass: 521.201 Da
• Monoisotopic Mass: 521.201 Da
• Topological Polar Surface Area: 170.000 Ų
• Heavy Atom Count: 37
• Formal Charge: 0
• Complexity: 823.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1