AR AR for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Potassium phosphate tribasic is a reagent with a very high buffering capacity. Widely used in molecular biology, biochemistry, and chromatography. Potassium phosphate occurs in several forms: monobasic (KH2PO4), dibasic (K2HPO4), and tribasic (K3PO4). Neutral potassium phosphate buffer solutions may be prepared with a mixture of the monobasic and dibasic forms to varying degrees, depending on the desired pH. Potassium Phosphate buffers are very useful in numerous applications, but with the following limitations; precipitation of Ca2+ and Mg2+, inhibition of restriction enzyme activity, and interference in DNA ligation or bacterial transformation protocols. Has been used to study the effects of freezing and thawing on the stability of proteins sensitive to conformational changes; it was found that potassium phosphate buffers offered improved pH stability as opposed to sodium phosphate buffers. Potassium Phosphate has also been used for the extraction of keratohyalin protein from bovine tissue.
A reagent with very high buffering capacity widely used in molecular biology
| Pubchem Sid | 504769131 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504769131 |
| Canonical Smiles | O.[O-]P(=O)([O-])[O-].[K+].[K+].[K+] |
| Isomeric SMILES | O.[O-]P(=O)([O-])[O-].[K+].[K+].[K+] |
| Alternate CAS | 27176-10-9 |
| PubChem CID | 22031701 |
| Molecular Weight | 212.27 (as Anhydrous) |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Solubility | Soluble in water (100 mg/mL). Insoluble in alcohol. |
|---|---|
| Sensitivity | moisture sensitive |
| Molecular Weight | 230.280 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 0 |
| Exact Mass | 229.855 Da |
| Monoisotopic Mass | 229.855 Da |
| Topological Polar Surface Area | 87.300 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 36.800 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 5 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View AR grade guide →
G2222580