Prilocaine - Moligand™, 10mM in DMSO , Sodium channel alpha subunit blocker, CAS No.721-50-6, Sodium channel alpha subunit blocker

CAS: 721-50-6 Cat. No.: P408848 Summenformel: C₁₃H₂₀N₂O Molekulargewicht: 220.31 EG-Nummer: 211-957-0

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

NSC 40027 | 2-(propylamino)-N-o-tolylpropanamide

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

Prilocaine Prilocaine (NSC 40027) is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyme

NSC 40027 | 2-(propylamino)-N-o-tolylpropanamide

Spezifikationen & Reinheit

Moligand™, 10mM in DMSO

Biochemische und physiologische Mechanismen

Prilocaine (NSC 40027) is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

BLOCKER

Mechanismus der Wirkung

Sodium channel alpha subunit blocker

Produkteigenschaften

• ALogP: 2.1

Namen und Kennungen

• Isomere SMILES: CCCNC(C)C(=O)NC1=CC=CC=C1C
• Molekulargewicht: 220.31
• Reaxy-Rn: 2108498
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2108498&ln=

Referenzen

1. Shuhan Wang, Yaqi Yang, Jiahong Lin, Weishan Zhang, Cuizhu Yang, Runheng Zhang, Chang Zhou, Li Zhang, Xin Wang, Jing Liu, Xiaobao Jin, Yuxin Ma.  (2025)  Astragalin actives autophagy and inhibits apoptosis of astrocytes in AD mice via down-regulating Fas/Fasl-VDAC1 pathway.  FREE RADICAL BIOLOGY AND MEDICINE,      [PMID:40032030] [10.1016/j.freeradbiomed.2025.02.047]

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 721-50-6, the molecular formula is C13H20N2O, and the molecular weight is 220.31 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.