Proparacaine HCl - 10mM in DMSO , Sodium channel alpha subunit blocker, CAS No.5875-06-9, Sodium channel alpha subunit blocker

CAS: 5875-06-9 Cat. No.: P409282 Summenformel: C16H26N2O3·HCl Molekulargewicht: 330.85 EG-Nummer: 227-541-7
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GRADE & PURITY 10mM in DMSO
Synonyms
3-​amino-​4-​propoxy-benzoic acid-2-​(diethylamino)​ethyl ester, hydrochloride (1:1)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Deutschland (EU)
USA*
Price
Qty
1ml
P409282-1ml
—
1 Auf Lager

208,17€

303,62€
Speichern 95,45 € (31.44%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Information

Proparacaine HCl Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.
In vitro

Proparacaine is more potent and less toxic than cocaine. Proparacaine significantly increases in FHV-1 (P < 0.01), C. felis, and 28S rDNA Ct values when fusidic acid is used.

In vivo

Proparacaine inhibits corneal epithelial migration and adhesion through alteration of the actin cytoskeleton. Proparacaine acts like bupivacaine or lidocaine and produces dose-related spinal blockades of motor function, proprioception and nociception. Intrathecal proxymetacaine also produces longer sensory blockade than motor blockade.
Cell Data

cell lines:Human colon carcinoma cell lines SW480, SW620, and HCT116, normal colonic epithelial cell line CCD-841Co

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonyme
3-​amino-​4-​propoxy-benzoic acid-2-​(diethylamino)​ethyl ester, hydrochloride (1:1)
Spezifikationen & Reinheit
10mM in DMSO
Biochemische und physiologische Mechanismen
Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.
Storage
Store at -80°C
Verschickt in
Dry ice packs + Cold packs
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Aktionsart
BLOCKER
Mechanismus der Wirkung
Sodium channel alpha subunit blocker
Namen und Kennungen
Isomere SMILES
CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N.Cl
RTECS
DG3065000
Molekulargewicht
330.85
Reaxy-Rn
3754950
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3754950&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemische und physikalische Eigenschaften
Schmelzpunkt (°C)184 °C
Lösungsrechner
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Häufig gestellte Fragen

How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 5875-06-9, the molecular formula is C16H26N2O3·HCl, and the molecular weight is 330.85 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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