PROTAC EGFR degrader 4 - ≥99% , CAS No.2882845-50-1

CAS: 2882845-50-1 Cat. No.: P1423526 Summenformel: C55H70N12O4S Molekulargewicht: 995.29
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GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
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Size
Deutschland (EU)
USA*
Price
Qty
1mg
P1423526-1mg
Auf Bestellung · 8–12 Wochen
261,10€
5mg
P1423526-5mg
Auf Bestellung · 8–12 Wochen
794,76€
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

PROTAC EGFR degrader 4 is a potent PROTAC targeting mutant EGFR.PROTAC EGFR degrader 4 induces EGFR del19 and EGFR L858R/T790M degradation with DC 50 s of 0.51 and 126 nM, respectively. PROTAC EGFR degrader 4 significantly inhibits growth of HCC827 and H1975 cell lines with IC 50 s of 0.83 and 203.1 nM, respectively. Induced EGFR degradation is related to autophagy.

Specifications

Spezifikationen & Reinheit
≥99%
Storage
Store at 2-8°C,Protected from light,Argon charged
Verschickt in
Wet ice
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Aktionsart
INHIBITOR
Reinheit
≥99%
Namen und Kennungen
Molekulargewicht 995.29

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Lösungsrechner
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