Pyridone 6 - Moligand™, 10 mM in DMSO , CAS No.457081-03-7

CAS: 457081-03-7 Cat. No.: P1497038 Summenformel: C₁₈H₁₆FN₃O Molekulargewicht: 309.34 PubChem CID: 5494425

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC 50 s of 1 nM for JAK2 and TYK2 , 5 nM for JAK3 , and 15 nM for JAK1 , while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases.

Specifications

Spezifikationen & Reinheit

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Namen und Kennungen

Isomere SMILES

CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O

PubChem CID

5494425

Molekulargewicht

309.34