R18 TFA, CAS No.211364-78-2(free)

CAS: 211364-78-2(free) Cat. No.: R407695 Summenformel: C₁₀₁H₁₅₇N₂₇O₂₉S₃·C₂HF₃O₂ Molekulargewicht: 2423.69

GRADE & PURITY ≥98%

Übersicht

application：

R18 trifluoroacetate has been used to treat 12-d-old or 14-d-old Super:C-repeat-binding factors (CBFs)-Myc plants for CBF protein immunoblots to study the effect of R18 on CBF3 degradation in planta.

product description：

R18 trifluoroacetate is a nonphosphorylated peptide. This peptide was originally identified as a high-affinity 14-3-3 ligand by phage display.

Specifications

Product Name

R18 TFA, CAS No.211364-78-2(free)

Synonyme

(3S,4Z,6S,7Z,9S,10Z,12S,13Z,15S,16Z,18S,19Z,21S,22Z,24S)-12-((1H-indol-3-yl)methyl)-18-(carboxymethyl)-24-((1Z,3S,4Z,6S,7Z,9S,10Z,12R,13Z,15S)-15-((S)-2-carboxypyrrolidine-1-carbonyl)-1,4,7,10,13-pentahydroxy-6-(2-hydroxy-2-iminoethyl)-12-(mercaptomethyl)

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

R18 is a competitive inhibitor of the 14-3-3 scaffolding proteins. It binds to the general binding groove of 14-3-3. R18 blocks 14-3-3 interaction with most or all of its client proteins. R18 (PHCVPRDLSWLDLEANMCLP), a competitive inhibitor of 14-3-3 scaff

Sequenz

Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro

CAS

211364-78-2(free)

Molekültyp

Peptide

Lagerung und Versand

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 211364-78-2(free).

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.