Recombinant C4d Antibody - Primärer Antikörper, specific to C4d, Rabbit IgG

Cat. No.: Ab092216

QUALITÄT & REINHEIT Recombinant, ExactAb™, Validated, 0.12 mg/mL

Application

IHC

Host species

Kaninchen

Reactive species

Mensch

Isotype

Rabbit IgG

Clone Number

MyR1-C4d

Conjugation

Unconjugated

Übersicht

Rabbit anti Human C4d Antibody, Recombinant (MyR1-C4d), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Protein Function
C4 plays a central role in the activation of the classical pathway of the complement system. It is processed by activated C1 which removes from the alpha chain the C4a anaphylatoxin. The remaining alpha chain fragment C4b is the major activation product and is an essential subunit of the C3 convertase (C4b2a) and the C5 convertase (C3bC4b2a) enzymes of the classical complement pathway.
Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Spezifikationen

Product Name

Recombinant C4d Antibody - Primärer Antikörper, specific to C4d, Rabbit IgG

Synonyme

acidic C4 antibody|Acidic complement C4 antibody|basic C4 antibody|basic complement C4 antibody|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody|C4 antibody|C4, chido form antibody|C4, Rodgers form antibody|C4-1 antibody|C4a anaphylatoxin antibody|C4A antibody|C4A2 antibody|C4A3 antibody|C4A4 antibody|C4A6 antibody|C4AD antibody|C4b antibody|C4B_2 antibody|C4B1 antibody|C4B12 antibody|C4B2 antibody|C4B3 antibody|C4B5 antibody|C4BD antibody|C4d antibody|C4d fragment antibody|C4F antibody|C4S antibody|CH antibody|Chido form of C4 antibody|CO4 antibody|Complement C4 A antibody|Complement C4 B antibody|Complement C4 gamma chain antibody|complement C4-A antibody|complement C4-B antibody|complement C4-B-like antibody|complement C4B1a antibody|Complement component 4A antibody|complement component 4A (Rodgers blood group) antibody|Complement component 4B antibody|complement component 4B (Chido blood group) antibody|complement component 4B (Chido blood group), copy 2 antibody|complement component 4B (Chido blood group)-like antibody|Complement component 4F antibody|Complement component 4S antibody|CPAMD2 antibody|CPAMD3 antibody|DADB-112B14.11 antibody|MGC164979 antibody|RG antibody|Rodgers form of C4 antibody|RG|CO4|C4A2|C4A3|C4A4|C4A6|C4AD|CPAMD2|CH|CPAMD3

Spezifikationen & Reinheit

ExactAb™, Validated, Recombinant, 0.12 mg/mL

Wirtsspezies

Kaninchen

Spezifität

C4d

Positive Kontrolle

IHC: Human tonsil tissue.

Konjugation

Unconjugated

Note

ExactAb™, Recombinant, Validated

Isotyp

Rabbit IgG

Lichterketten-Typ

kappa

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Protein A purified

Konzentration

0.12 mg/mL

Product Line

Biologische Produkte

Lagerung und Versand

Form

Liquid

Storage

Store at 2-8°C,Do not freeze

Verschickt in

Wet ice,Do not freeze

Stabilität und Lagerung

Store at 2-8°C long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

IHC: Recombinant C4d Antibody (Ab092216) ​

Recombinant C4d Antibody (Ab092216) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling C4d with Recombinant C4d Antibody (Ab092216) at 1/100 dilution. The section was incubated with Ab092216 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Anwendung

Anwendung

Dilution info

IHC

1/100 - 1/200

Zugehörige Ziele (menschlich)

C4B Tbio Complement C4-B (0 Activities)

Discover Target: C4B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C4A Tbio Complement C4-A (0 Activities)

Discover Target: C4A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)