Recombinant Human IL-34 Protein, ≥95% (SDS-PAGE)

Cat. No.: rp147566
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
Expression System
CHO
Accession #
Q6ZMJ4
Protein Tag
C-His
Expression system
CHO
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Measured in a cell proliferation assay using human peripheral blood mononuclear cell. The ED50 for this effect is 2-8 ng/mL.
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10μg
rp147566-10μg
6
$263.90
50μg
rp147566-50μg
2
$413.90
100μg
rp147566-100μg
3
$661.90
Enter a quantity for the sizes you want to add.
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Why this grade

Animal Free,Carrier Free,Bioactive,ActiBioPure™,Azide Free,High Performance,His-Tag,≥95%(SDS-PAGE) ActiBioPure™,Animal Free,Azide Free,Bioactive,Carrier Free,High Performance,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Purity
≥ 95% SDS-PAGE.
Function
Interleukin-34 (IL-34) is a protein that promotes the proliferation, survival and differentiation of monocytes and macrophages. It also promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. IL-34 plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.

Specifications

Product Name
Recombinant Human IL-34 Protein, ≥95% (SDS-PAGE)
Synonyms
C16orf77 | IL34 | IL-34 | interleukin 34 | Chromosome 16 open reading frame 77 | FPT025 | IL 34 | IL34_HUMAN | Interleukin-34 | Interleukin34 | MGC34647 | IL-34
Grade
ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, High Performance, His Tag
Specifications & Purity
Animal Free, Carrier Free, Bioactive, ActiBioPure™, Azide Free, High Performance, His-Tag, ≥95%(SDS-PAGE)
Purity
≥95% (SDS-PAGE)
Bioactivity
Measured in a cell proliferation assay using human peripheral blood mononuclear cell. The ED50 for this effect is 2-8 ng/mL.
Endotoxin Concentration
<1.0 EU/μg
Expression System
CHO
Species
Human
Amino Acids
21-242 aa
Sequence
NEPLEMWPLTQNEECTVTGFLRDKLQYRSRLQYMKHYFPINYKISVPYEGVFRIANVTRLQRAQVSERELRYLWVLVSLSATESVQDVLLEGHPSWKYLQEVQTLLLNVQQGLTDVEVSPKVESVLSLLNAPGPNLKLVRPKALLDNCFRVMELLYCSCCKQSSVLNWQDCEVPSPQSCSPEPSLQYAATQLYPPPPWSPSSPPHSTGSVRPVRAQGEGLLPAHHHHHHHHHH
Protein Tag
C-His
Accession #
Predicted molecular weight
26.7 kDa
SDS-PAGE
37.9 kDa, under reducing conditions; 36.2 kDa, under non-reducing conditions.
Note
This product is about to be sold out and removed from the shelves. The replacement product is rp168119.
Molecule Type
Protein
Storage and Shipping
Shape
Lyophilized
Reconstitution
It is recommended that sterile water be added to the vial to preparea stock solution of 0.25mg/mL.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Samples are stable for twelve months from date of receipt at -20℃ to -80℃. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Recombinant Human IL-34 Protein (rp147566) - Protein Bioactivity
Measured in a cell proliferation assay using human peripheral blood mononuclear cell. The ED₅₀ for this effect is 2.0 - 8.0 ng/mL.

Recombinant Human IL-34 Protein (rp147566) - SDS-PAGE
3 μg/lane of Recombinant Human IL-34 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 37.9 kDa under reducing conditions and 36.2 kDa under non-reducing conditions.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0102330Certificate of AnalysisJun 18, 2026 rp147566
ZJ24F0102332Certificate of AnalysisJun 18, 2026 rp147566
ZJ24F0102344Certificate of AnalysisJun 18, 2026 rp147566
Documents & Articles
Solution Calculators
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