Recombinant Myelin Basic Protein Antibody - Primärer Antikörper, specific to Myelin Basic Protein, Rabbit IgG

Cat. No.: Ab116662

GRADE & PURITY Carrier Free, Recombinant, ExactAb™, Validated, 0.075 mg/mL

Application

IHC

Host species

Kaninchen

Reactive species

Mensch

Isotype

Rabbit IgG

Clone Number

EP207

Conjugation

Unconjugated

Übersicht

Rabbit anti Human Myelin Basic Protein Antibody, Recombinant (EP207), could be used for IHC and so on.
Application
IHC: 1/50-1/100
Protein Function
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

Specifications

Product Name

Recombinant Myelin Basic Protein Antibody - Primärer Antikörper, specific to Myelin Basic Protein, Rabbit IgG

Synonyme

GDB antibody | Golli MBP antibody | Golli MBP | myelin basic protein antibody | Hemopoietic MBP antibody | HMBPR antibody | HUGO antibody | MBP antibody | MBP_CAVPO antibody | MBP_HUMAN antibody | MGC99675 antibody | MLD antibody | Myelin A1 protein antib

Spezifikationen & Reinheit

ExactAb™, Validated, Carrier Free, Recombinant, 0.075 mg/mL

Wirtsspezies

Kaninchen

Spezifität

Myelin Basic Protein

Immunogen

A synthetic peptide corresponding to residues of Myelin Basic Protein (AA 150-250).

Positive Kontrolle

IHC: Human glioma tissue.

Konjugation

Unconjugated

Note

Carrier Free, ExactAb™, Recombinant, Validated

Isotyp

Rabbit IgG

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Protein A purified

Konzentration

0.075 mg/mL

Product Line

Biologische Produkte

Lagerung und Versand

Form

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Verschickt in

Ice chest + Ice pads

Stabilität und Lagerung

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

IHC: Recombinant Myelin Basic Protein Antibody (Ab116662) ​

Recombinant Myelin Basic Protein Antibody (Ab116662) - IHC
Immunohistochemistry analysis of paraffin-embedded human glioma tissue labelling Myelin Basic Protein with Recombinant Myelin Basic Protein Antibody (Ab116662) at 1/100 dilution. The section was incubated with Ab116662 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Anwendung

Anwendung

Dilution info

IHC

1/50 - 1/100

Zugehörige Ziele (menschlich)

MBP Tbio Myelin basic protein (0 Activities)

Discover Target: MBP

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Häufig gestellte Fragen

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Recombinant mean?

Recombinant is a defined analytical purity tier suitable for workflows requiring a specific validated property. It specifies a minimum assay percentage, controlled limits on common impurities (water, heavy metals, residue on ignition), and lot-to-lot consistency. Recombinant is one of several purity tiers — choose based on the sensitivity and regulatory requirements of your method.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Recombinant Myelin Basic Protein Antibody); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.