RMC-6291 - ≥99% , CAS No.2641998-63-0

CAS: 2641998-63-0 Cat. No.: R646965 Summenformel: C₅₅H₇₈FN₉O₈ Molekulargewicht: 1012.26

GRADE & PURITY ≥99%

Synonyms

Elironrasib

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

RMC-6291 is an orally active and covalent inhibitor of KRAS G12C (ON) . RMC-6291 forms a tri-complex within tumor cells between KRAS G12C (ON) and cyclophilin A (CypA). Thus, RMC-6291 prevents KRAS G12C (ON) from signaling via steric blockade of RAS effector binding. RMC-6291 elicits deep and durable suppression on RAS pathway activity in KRAS G12C tumor models

Form:Solid

IC50& Target:KRAS(G12C)

Specifications

Synonyme

Elironrasib

Spezifikationen & Reinheit

≥99%

Biochemische und physiologische Mechanismen

RMC-6291 is an orally active and covalent inhibitor of KRAS G12C (ON) . RMC-6291 forms a tri-complex within tumor cells between KRAS G12C (ON) and cyclophilin A (CypA). Thus, RMC-6291 prevents KRAS G12C (ON) from signaling via steric blockade of RAS effec

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥99%

Namen und Kennungen

Kanonisches Lächeln

C[C@H](OC)C(N=CC=C1)=[C@@]1[C@](N2CC)=C(CC(C)(C)COC([C@H]3NN(C([C@@H](NC([C@H](C(C)C)N(C(C4(F)CCN(C(C#CC(N(C)C)(C)C)=O)CC4)=O)C)=O)C[C@H]5CN6CCO5)=O)CCC3)=O)C7=C2C=CC6=C7

Molekulargewicht

1012.26

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 100 mg/mL (98.79 mM; Need ultrasonic)