RSC 133 - Moligand™, ≥98% , CAS No.1418131-46-0

CAS: 1418131-46-0 Cat. No.: R341345 Summenformel: C₁₈H₁₅N₃O₂ Molekulargewicht: 305.33 EG-Nummer: 808-553-7 PubChem CID: 24799203

QUALITÄT & REINHEIT Moligand™, ≥98%

Synonyms

RSC133, >=98% (HPLC) | MS-24410 | EC-000.2551 | SCHEMBL2085437 | AKOS040745336 | 3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide | HYUDSQGICKAEGE-CMDGGOBGSA-N | 1064711-57-4 | rsc133 | RSC-133 | HY-12310 | RSC 133 | 3-[[(2E)-3-(1H-Indol-3-yl)-1-oxo-

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells.

Spezifikationen

Synonyme

RSC133, >=98% (HPLC) | MS-24410 | EC-000.2551 | SCHEMBL2085437 | AKOS040745336 | 3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide | HYUDSQGICKAEGE-CMDGGOBGSA-N | 1064711-57-4 | rsc133 | RSC-133 | HY-12310 | RSC 133 | 3-[[(2E)-3-(1H-Indol-3-yl)-1-oxo-

Spezifikationen & Reinheit

Moligand™, ≥98%

Biochemische und physiologische Mechanismen

RSC133 is an epigenetic modulator that effectively enhances reprogramming of human somatic cells and maintenance of human stem cell pluripotency. RSC133 is an epigenetic modulator that effectively enhances reprogramming of human somatic cells and maintena

Storage

Protected from light,Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Reinheit

≥98%

Namen und Kennungen

Pubchem Sid

528766915

Kanonisches Lächeln

C1=CC=C2C(=C1)C(=CN2)C=CC(=O)NC3=CC=CC(=C3)C(=O)N

IUPAC Name

3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide

InChIKey

HYUDSQGICKAEGE-CMDGGOBGSA-N

INCHI

1S/C18H15N3O2/c19-18(23)12-4-3-5-14(10-12)21-17(22)9-8-13-11-20-16-7-2-1-6-15(13)16/h1-11,20H,(H2,19,23)(H,21,22)/b9-8+

Isomere SMILES

C1=CC=C2C(=C1)C(=CN2)/C=C/C(=O)NC3=CC=CC(=C3)C(=O)N

WGK Deutschland

3

PubChem CID

24799203

Molekulargewicht

305.33

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Klasse Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Klasse: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Acylaminobenzoic acid and derivatives
• Alternative Parents: Indoles Benzamides Anilides N-arylamides Benzoyl derivatives Substituted pyrroles Heteroaromatic compounds Secondary carboxylic acid amides Primary carboxylic acid amides Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Acylaminobenzoic acid or derivatives - Benzamide - Indole - Indole or derivatives - Anilide - Benzoyl - N-arylamide - Substituted pyrrole - Pyrrole - Heteroaromatic compound - Secondary carboxylic acid amide - Primary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as acylaminobenzoic acid and derivatives. These are derivatives of amino benzoic acid derivatives where the amine group is N-acylated.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Empfindlichkeit: light sensitive
• Molekulargewicht: 305.300 g/mol
• XLogP3: 2.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 305.116 Da
• Monoisotopic Mass: 305.116 Da
• Topological Polar Surface Area: 88.000 Ų
• Heavy Atom Count: 23
• Formal Charge: 0
• Complexity: 477.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1