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SGI-1776 free base - Moligand™, ≥98% , Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kin, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene;

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SGI-1776 free base - Moligand™, ≥98% , Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kin, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene;

SKU: S126376
Availability: InStock

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S126376

Artikel für gruppiertes Produkt
Produktname	Menge
[S126376-5mg] SGI-1776 free base (5mg) 112,72 €
[S126376-10mg] SGI-1776 free base (10mg) 169,99 €
[S126376-50mg] SGI-1776 free base (50mg) 597,79 €

Novel ATP competitive inhibitor of Pim1

SGI-1776 is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin
A potent apoptotic that targets Pim and FLT3 in AML and CLL cells.

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Weitere Informationen
CAS	1025065-69-3
Synonyme	N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[2,1-f]pyridazin-6-amine \| Imidazo[1,2-b]pyridazin-6-amine, N-[(1-methyl-4-piperidinyl)methyl]-3-[3-(trifluoromethoxy)phenyl]- \| NSC800883 \| NSC-800883 \| SB19298 \| AC-28432 \| N-((1-Me
Spezifikationen & Reinheit	Moligand™, ≥98%
Storage	Store at -20°C
Verschickt in	Ice chest + Ice pads
Product Description	SGI-1776 is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin A potent apoptotic that targets Pim and FLT3 in AML and CLL cells.
Pubchem Sid	528767088
Löslichkeit	DMSO ≥80mg/mL Water <1.2mg/mL Ethanol ≥80mg/mL
PubChem CID	24795070

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