ShK-Dap22, CAS No.220384-25-8

CAS: 220384-25-8 Cat. No.: S288250 Molecular Weight: 4012.7 EC Number: 686-476-6 PubChem CID: 90488816
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Size
Status
Price
Qty
100μg
S288250-100μg
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Product Name
ShK-Dap22, CAS No.220384-25-8
Synonyms
ShK-Dap22 | (DAP22)-SHK | AKOS024457486 | PD079453
Biochemical and Physiological Mechanisms
Extremely potent KV1.3 channel blocker (Kd= 23 pM for mKV1.3 currents). Selective for KV1.3 over other mammalian potassium channels (IC50values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000
Sequence
RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC(Modifications: Disulfide bridges: 3-35, 12-28, 17-32), X= Dap)
CAS
220384-25-8
Molecule Type
Peptide
Storage and Shipping
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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