SHR902275 , CAS No.2695506-82-0

CAS: 2695506-82-0 Cat. No.: S1436386 Summenformel: C₂₆H₂₃F₃N₄O₄ Molekulargewicht: 512.48

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Übersicht

SHR902275 is a potent, selective, and orally active RAF inhibitor targeting RAS mutant cancers. SHR902275 has IC 50 s of 1.6 nM, 10 nM, and 5.7 nM for cRAF, bRAF wt , and bRAF V600E , respectively. SHR902275 shows cell growth inhibition with GI 50 s of 1.5 and 0.17 nM, 0.4 nM and 0.32 nM for H358, A375, Calu6, and SK-MEL2 cells respectively.

Specifications

Storage

Store at -20°C

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Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Namen und Kennungen

• Molekulargewicht: 512.48