≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
product description：
P-141 is a specific MDM2 inhibitor. SP-141 promotes MDM2 auto-ubiquitination and degradation. SP-141 in potential for cancer research.
| Canonical Smiles | COC1=CC2=C(C=C1)NC3=C2C=CN=C3C4=CC=CC5=CC=CC=C54 |
|---|---|
| IUPAC Name | 6-methoxy-1-naphthalen-1-yl-9H-pyrido[3,4-b]indole |
| InChIKey | AABFWJDLCCDJJN-UHFFFAOYSA-N |
| INCHI | 1S/C22H16N2O/c1-25-15-9-10-20-19(13-15)18-11-12-23-21(22(18)24-20)17-8-4-6-14-5-2-3-7-16(14)17/h2-13,24H,1H3 |
| Isomeric SMILES | COC1=CC2=C(C=C1)NC3=C2C=CN=C3C4=CC=CC5=CC=CC=C54 |
| PubChem CID | 59620153 |
| Molecular Weight | 324.38 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Alkaloids and derivatives |
| Class | Harmala alkaloids |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Harmala alkaloids |
| Alternative Parents | Beta carbolines Naphthalenes Indoles Anisoles Alkyl aryl ethers Pyridines and derivatives Pyrroles Heteroaromatic compounds Azacyclic compounds Organonitrogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Harman - Beta-carboline - Pyridoindole - Naphthalene - Indole - Indole or derivatives - Anisole - Phenol ether - Alkyl aryl ether - Pyridine - Benzenoid - Heteroaromatic compound - Pyrrole - Organoheterocyclic compound - Azacycle - Ether - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as harmala alkaloids. These are compounds with a structure based on harmaline, harmine, harmalol, harman or a derivative of those parents. These parents are beta-carbolines, consisting of a pyrimidine fused to the pyrrole moiety of an indole to form a pyrido[3,4-b]indole. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2518146 | Certificate of Analysis | Nov 24, 2025 | S288439 |
| J2120019 | Certificate of Analysis | Aug 09, 2024 | S288439 |
| J2120020 | Certificate of Analysis | Aug 09, 2024 | S288439 |
| J2120021 | Certificate of Analysis | Aug 09, 2024 | S288439 |
| J2120022 | Certificate of Analysis | Aug 09, 2024 | S288439 |
| J2120023 | Certificate of Analysis | Aug 09, 2024 | S288439 |
| J2120024 | Certificate of Analysis | Aug 09, 2024 | S288439 |
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 32.44, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 32.44, Max Conc. mM: 100 |
|---|---|
| Molecular Weight | 324.400 g/mol |
| XLogP3 | 5.200 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 324.126 Da |
| Monoisotopic Mass | 324.126 Da |
| Topological Polar Surface Area | 37.900 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 469.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Qi Chen, Ziwei Huang, Jing Chen, Xiaoyu Tian, Rong Zhang, Qi Liang, Zhongqiu Liu, Yuanyuan Cheng. (2024) Notoginsenoside R1 attenuates ischemic heart failure by modulating MDM2/β arrestin2-mediated β2-adrenergic receptor ubiquitination. BIOMEDICINE & PHARMACOTHERAPY, [PMID:38955084] [10.1016/j.biopha.2024.117004] |
