Sulbactam sodium - ≥98% , Bacterial beta-lactamase TEM inhibitor, CAS No.69388-84-7, Bacterial beta-lactamase TEM inhibitor

CAS: 69388-84-7 Cat. No.: E129334 Summenformel: C₈H₁₀NO₅S·Na Molekulargewicht: 255.22 EG-Nummer: 273-984-4

GRADE & PURITY ≥98%

Synonyms

NKZMPZCWBSWAOX-IBTYICNHSA-M | SODIUM (2S-CIS)-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE 4,4-DIOXIDE | Sulbactam Sodium, Antibiotic for Culture Media Use Only | DKQ4T82YE6 | SULBACTAM SODIUM [MART.] | Sodium 1,1-dioxopenicillanate

Storage

Store at 2-8°C

Shipped In

Wet ice

Übersicht

Sulbactam sodium (Unasyn) is an irreversible β-lactamase inhibitor.
A β-lactamase inhibitor that has similar characteristics as ampicillin.

Specifications

Synonyme

NKZMPZCWBSWAOX-IBTYICNHSA-M | SODIUM (2S-CIS)-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE 4,4-DIOXIDE | Sulbactam Sodium, Antibiotic for Culture Media Use Only | DKQ4T82YE6 | SULBACTAM SODIUM [MART.] | Sodium 1,1-dioxopenicillanate

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

Sulbactam sodium salt is a β-lactamase inhibitor that has similar characteristics as ampicillin.Irreversible β-lactamase inhibitor (IC 50 = 0.02 - 1.9 μM). Increases the activity of β-lactam antibiotics. Active in vitro and in vivo .

Storage

Store at 2-8°C

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Mechanismus der Wirkung

Bacterial beta-lactamase TEM inhibitor

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥98%

Namen und Kennungen

Pubchem Sid

508816313

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508816313

Kanonisches Lächeln

CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])C.[Na+]

IUPAC Name

sodium;(2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChIKey

NKZMPZCWBSWAOX-IBTYICNHSA-M

INCHI

1S/C8H11NO5S.Na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6H,3H2,1-2H3,(H,11,12);/q;+1/p-1/t5-,6+;/m1./s1

Isomere SMILES

CC1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])C.[Na+]

Molekulargewicht

255.22

Reaxy-Rn

1137390

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1137390&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Ebene5 Amino acids and derivatives
          • Ebene6 Alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Alpha amino acids and derivatives
• Alternative Parents: Penams Thiazolidines Tertiary carboxylic acid amides Sulfones Carboxylic acid salts Azetidines Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organonitrogen compounds Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic cations
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Alpha-amino acid or derivatives - Penam - Beta-lactam - Sulfone - Tertiary carboxylic acid amide - Thiazolidine - Azetidine - Carboxamide group - Carboxylic acid salt - Lactam - Organic alkali metal salt - Azacycle - Monocarboxylic acid or derivatives - Carboxylic acid - Organoheterocyclic compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organic salt - Organic sodium salt - Organic cation - Aliphatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO 3 mg/mL Water 51 mg/mL Ethanol
• Empfindlichkeit: Hygroscopic
• Molekulargewicht: 255.230 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 255.018 Da
• Monoisotopic Mass: 255.018 Da
• Topological Polar Surface Area: 103.000 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 452.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3